There is growing evidence that vascular pathology plays a role in the onset and/or
progression of an underlying joint disease: osteoarthritis deformans (DOA). Possible …

Transforming growth factor-β (TGFβ) is a pleiotropic cytokine that is important in the
regulation of joint homeostasis and disease. TGFβ signalling is induced by loading and has …

Subchondral bone plays a critical role in the pathogenesis of osteochondral disease across
veterinary species. The subchondral bone is highly adaptable, with the ability to model and …

There is mounting evidence that vascular pathology plays a role in the initiation and/or
progression of the major disease of joints: osteoarthritis (OA). Potential mechanisms are …

Osteoarthritis (OA) is a potentially disabling disease whose progression is dependent on
several risk factors. OA management usually involves the use of non-steroidal anti …

Osteoarthritis (OA), the most common form of arthritis, is a potentially devastating joint
disease, affecting 27 million US adults. Its pathophysiology is marked by a gradual …

OBJECTIVE: To examine the associations between meniscal tear, knee structure,
osteoarthritis (OA) risk factors, radiographic change, and symptoms in a largely non …

Osteoarthritis is a chronic disease characterised by irreversible damage to joint structures,
including loss of articular cartilage, osteophyte formation, alterations in the subchondral …

Objectives. Earlier studies suggest the involvement of osteoprotegerin (OPG), RANK and
RANK ligand (RANKL) in OA subchondral bone metabolism; however, few studies have …

Early in the pathological process of osteoarthritis (OA), subchondral bone remodelling,
which is related to altered osteoblast metabolism, takes place. In the present study, we …