The tremendous biomedical potential of bacterial extracellular vesicles

J Xie, Q Li, F Haesebrouck, L Van Hoecke… - Trends in …, 2022 - cell.com
Bacterial extracellular vesicles (bEVs) are nano-sized, lipid membrane-delimited particles
filled with bacteria-derived components. They have important roles in the physiology and …

Bacterial membrane vesicles for vaccine applications

N Krishnan, LJ Kubiatowicz, M Holay, J Zhou… - Advanced Drug Delivery …, 2022 - Elsevier
Vaccines have been highly successful in the management of many diseases. However,
there are still numerous illnesses, both infectious and noncommunicable, for which there are …

Bacterial outer membrane vesicles as potential biological nanomaterials for antibacterial therapy

W Huang, L Meng, Y Chen, Z Dong, Q Peng - Acta biomaterialia, 2022 - Elsevier
Antibiotic therapy is one of the most important approaches against bacterial infections.
However, the improper use of antibiotics and the emergence of drug resistance have …

Bacteria and bacterial derivatives as drug carriers for cancer therapy

Z Cao, J Liu - Journal of controlled release, 2020 - Elsevier
The application of bacteria and bacteria-derived membrane vesicles (MVs) has promising
potential to make a great impact on the development of controllable targeted drug delivery …

Progress of engineered bacteria for tumor therapy

JX Fan, MT Niu, YT Qin, YX Sun, XZ Zhang - Advanced Drug Delivery …, 2022 - Elsevier
Recently, with the rapid development of bioengineering technology and nanotechnology,
natural bacteria were modified to change their physiological activities and therapeutic …

[HTML][HTML] Extracellular vesicles: Emerging tools as therapeutic agent carriers

S Liu, X Wu, S Chandra, C Lyon, B Ning, J Fan… - … Pharmaceutica Sinica B, 2022 - Elsevier
Extracellular vesicles (EVs) are secreted by both eukaryotes and prokaryotes, and are
present in all biological fluids of vertebrates, where they transfer DNA, RNA, proteins, lipids …

Harnessing engineered immune cells and bacteria as drug carriers for cancer immunotherapy

J Jiang, Y Huang, Z Zeng, C Zhao - ACS nano, 2023 - ACS Publications
Immunotherapy continues to be in the spotlight of oncology therapy research in the past few
years and has been proven to be a promising option to modulate one's innate and adaptive …

[HTML][HTML] Nanomaterials: small particles show huge possibilities for cancer immunotherapy

Z Chen, Z Yue, K Yang, S Li - Journal of Nanobiotechnology, 2022 - Springer
With the economy's globalization and the population's aging, cancer has become the
leading cause of death in most countries. While imposing a considerable burden on society …

Immunomodulatory roles and novel applications of bacterial membrane vesicles

WJ Gilmore, EL Johnston, L Zavan, NJ Bitto… - Molecular …, 2021 - Elsevier
Bacteria release extracellular vesicles (EVs) known as bacterial membrane vesicles (BMVs)
during their normal growth. Gram-negative bacteria produce BMVs termed outer membrane …

[HTML][HTML] Application of lipid nanovesicle drug delivery system in cancer immunotherapy

Y Ding, L Wang, H Li, F Miao, Z Zhang, C Hu… - Journal of …, 2022 - Springer
Immunotherapy has gradually emerged as the most promising anticancer therapy. In
addition to conventional anti-PD-1/PD-L1 therapy, anti-CTLA-4 therapy, CAR-T therapy, etc …