Stress-induced early flowering is mediated by miR169 in Arabidopsis thaliana

MY Xu, L Zhang, WW Li, XL Hu… - Journal of …, 2014 - academic.oup.com
Plants interact with their environment and they often flower earlier under stress conditions,
but how such stress-induced flowering is regulated remains poorly understood. Here …

[HTML][HTML] Regulation of aldo–keto reductases in human diseases

WD Chen, Y Zhang - Frontiers in pharmacology, 2012 - frontiersin.org
The aldo–keto reductases (AKRs) are a superfamily of NAD (P) H-linked oxidoreductases,
which reduce aldehydes and ketones to their respective primary and secondary alcohols …

[HTML][HTML] BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism

ZQ Wang, A Faddaoui, M Bachvarova, M Plante… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Previously, we have identified the branched chain amino-acid transaminase 1 (BCAT1)
gene as notably hypomethylated in low-malignant potential (LMP) and high-grade (HG) …

Cisplatin resistance in human cervical, ovarian and lung cancer cells

J Chen, C Solomides, H Parekh, F Simpkins… - Cancer chemotherapy …, 2015 - Springer
Purpose This study was performed to determine whether or not in cervical, ovarian and lung
cancer cell lines, free radicals (ROS) play a role in cisplatin cytotoxicity and activation of the …

Specific inhibition of NF-Y subunits triggers different cell proliferation defects

P Benatti, D Dolfini, A Vigano, M Ravo… - Nucleic acids …, 2011 - academic.oup.com
Regulated gene expression is essential for a proper progression through the cell cycle. The
transcription factor NF-Y has a fundamental function in transcriptional regulation of cell cycle …

Pro‐inflammatory signals induce 20α‐HSD expression in myometrial cells: A key mechanism for local progesterone withdrawal

L Nadeem, R Balendran, A Dorogin… - Journal of Cellular …, 2021 - Wiley Online Library
Metabolism of progesterone (P4) by the enzyme 20α hydroxysteroid dehydrogenase (20α‐
HSD) in myometrial cells is postulated to be a mechanism for P4 withdrawal, which occurs …

[HTML][HTML] Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis

M Zhang, X Hu, M Zhu, M Xu, L Wang - Scientific Reports, 2017 - nature.com
In plants, leaf is crucial for photosynthesis and respiration. Leaf area and quantity are
important for leaf vegetables to increase biomass. The process of leaf development involves …

[HTML][HTML] (−)-Oleocanthal as a dual c-MET-COX2 inhibitor for the control of lung cancer

AB Siddique, PCSR Kilgore, A Tajmim, SS Singh… - Nutrients, 2020 - mdpi.com
Lung cancer (LC) represents the topmost mortality-causing cancer in the US LC patients
have overall poor survival rate with limited available treatment options. Dysregulation of the …

Transactivation activity of human papillomavirus type 16 E6* I on aldo-keto reductase genes enhances chemoresistance in cervical cancer cells

P Wanichwatanadecha… - Journal of general …, 2012 - microbiologyresearch.org
The oncogenic E6 proteins produced by high-risk human papillomaviruses (HPVs) are
invariably expressed in cervical carcinomas and are multifunctional proteins capable of …

Ets1 and Elk1 transcription factors regulate cancerous inhibitor of protein phosphatase 2A expression in cervical and endometrial carcinoma cells

R Pallai, A Bhaskar, V Sodi, LM Rice - Transcription, 2012 - Taylor & Francis
Cancerous inhibitor of protein phosphatase 2A (CIP2A) has been identified as a proto-
oncogene that is overexpressed in various types of human cancers. CIP2A acts by inhibiting …