Hepcidin upregulation in lung cancer: a potential therapeutic target associated with immune infiltration

Y Fan, B Liu, F Chen, Z Song, B Han, Y Meng… - Frontiers in …, 2021 - frontiersin.org
Lung cancer has the highest death rate among cancers globally. Hepcidin is a fascinating
regulator of iron metabolism; however, the prognostic value of hepcidin and its correlation …

Risk score generated from CT-based radiomics signatures for overall survival prediction in non-small cell lung cancer

VH Le, QH Kha, TNK Hung, NQK Le - Cancers, 2021 - mdpi.com
Simple Summary Despite recent advancements in lung cancer treatment, individuals with
lung cancer have a dismal 5-year survival rate of only 15%. In patients with non-small cell …

Prognostic and immunological role of FAT family genes in non-small cell lung cancer

Z Feng, Y Yin, B Liu, Y Zheng, D Shi… - Cancer …, 2022 - journals.sagepub.com
Background The FAT atypical cadherin 1/2/3/4 (FAT1/2/3/4) has been linked to the
occurrence and development of various cancers. However, the prognostic and …

Clinically relevant stratification of lung squamous carcinoma patients based on ubiquitinated proteasome genes for 3P medical approach

J Yang, SY Ouedraogo, J Wang, Z Li, X Feng, Z Ye… - EPMA Journal, 2024 - Springer
Relevance The proteasome is a crucial mechanism that regulates protein fate and
eliminates misfolded proteins, playing a significant role in cellular processes. In the context …

[HTML][HTML] OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma

Y Wang, L Shi, Y He, W Gong, Y Cui, R Zuo, Y Wang… - Iscience, 2024 - cell.com
Lung adenocarcinoma (LUAD) is one of the leading causes of cancer-related death
worldwide. Epithelial-mesenchymal transition (EMT) plays an important role in malignant …

CHEK1: a hub gene related to poor prognosis for lung adenocarcinoma

Z Tan, M Chen, Y Wang, F Peng, X Zhu, X Li… - Biomarkers in …, 2022 - Taylor & Francis
Aim: The study aims to pinpoint hub genes and investigate their functions in order to gain
insightful understandings of lung adenocarcinoma (LUAD). Methods: Bioinformatic …

Prediction of Responsiveness to PD-L1/PD-1 Inhibitors Using miRNA Profiles Associated With PD-L1 Expression in Lung Adenocarcinoma and Squamous Cell …

YW Koh, JH Han, S Haam, HW Lee - Anticancer Research, 2024 - ar.iiarjournals.org
Background/Aim: MicroRNAs (miRNAs) regulate programmed cell death ligand 1 (PD-L1)
and play a crucial role in tumor immune response. However, the relationship between …

Prognostic significance of iron metabolism related genes in human lung adenocarcinoma

P Li, X Wu, P Chen, Z Gu - Cancer Management and Research, 2023 - Taylor & Francis
Background Iron metabolism related genes participate in cell proliferation, cell growth, and
redox cycling in multiple cancers. Limited studies have revealed the roles and clinical …

Evaluation of Anticancer Effect of Lippia nodiflora Leaf Extract on Lung Cancer Cells

M Ashritha, P Elumalai… - Journal of …, 2021 - info.stmdigitallibrary.com
Background: Lung cancer, also known as bronchogenic carcinoma, is a kind of cancer that
begins in the lung parenchyma or inside the bronchi. In the United States, it is one of the top …

[HTML][HTML] An integrated model of FTO and METTL3 expression that predicts prognosis in lung squamous cell carcinoma patients

K Zhang, Z Han, H Zhao, S Liu… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Background Lung squamous cell carcinoma (LUSC) approximately accounts for a third of
lung cancers. However, the role of N6-methyladenosine (m6A) in LUSC remains largely …