Myocardial infarction triggers an intense inflammatory response that is essential for cardiac
repair, but which is also implicated in the pathogenesis of postinfarction remodelling and …

Hydrogen peroxide (H2O2) is an important metabolite involved in most of the redox
metabolism reactions and processes of the cells. H2O2 is recognized as one of the main …

Triple-negative breast cancer (TNBC) is treated with cytotoxic chemotherapy and is often
characterized by early relapse and metastasis. To form a secondary (recurrent and/or …

The high-fat, low-carbohydrate ketogenic diet (KD) is an established treatment for drug-
resistant epilepsy with a proven efficacy. The KD is being explored for Febrile Infection …

Four adenosine receptors have been cloned and characterized from several mammalian
species. The receptors are named adenosine A1, A2A, A2B, and A3. The A2A and A2B …

Murine macrophages are activated by interferon-γ (IFN-γ) and/or Toll-like receptor (TLR)
agonists such as bacterial endotoxin (lipopolysaccharide [LPS]) to express an inflammatory …

Adenosine is a key endogenous molecule that regulates tissue function by activating four G-
protein-coupled adenosine receptors: A1, A2A, A2B and A3. Cells of the immune system …

Adenosine, a purine nucleoside generated by the dephosphorylation of adenine
nucleotides, is a potent endogenous physiologic and pharmacologic regulator of many …

Inappropriate or prolonged inflammation is the main cause of many diseases; for this reason
it is important to understand the physiological mechanisms that terminate inflammation in …

The A2A adenosine receptor (A2AR) has been shown to be a critical and nonredundant
negative regulator of immune cells in protecting normal tissues from inflammatory damage …