AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treating Fields (TTFields)
A Shteingauz, Y Porat, T Voloshin… - Cell death & …, 2018 - nature.com
Abstract Tumor Treating Fields (TTFields), an approved treatment modality for glioblastoma,
are delivered via non-invasive application of low-intensity, intermediate-frequency …
are delivered via non-invasive application of low-intensity, intermediate-frequency …
[HTML][HTML] Tumor treating fields cause replication stress and interfere with DNA replication fork maintenance: Implications for cancer therapy
NK Karanam, L Ding, A Aroumougame, MD Story - Translational Research, 2020 - Elsevier
Tumor treating fields (TTFields) is a noninvasive physical modality of cancer therapy that
applies low-intensity, intermediate frequency, and alternating electric fields to a tumor …
applies low-intensity, intermediate frequency, and alternating electric fields to a tumor …
Association of Tumor Treating Fields (TTFields) therapy with survival in newly diagnosed glioblastoma: a systematic review and meta-analysis
MT Ballo, P Conlon, G Lavy-Shahaf, A Kinzel… - Journal of Neuro …, 2023 - Springer
Abstract Purpose Tumor Treating Fields (TTFields) therapy, an electric field-based cancer
treatment, became FDA-approved for patients with newly diagnosed glioblastoma (GBM) in …
treatment, became FDA-approved for patients with newly diagnosed glioblastoma (GBM) in …
Tumor-treating fields elicit a conditional vulnerability to ionizing radiation via the downregulation of BRCA1 signaling and reduced DNA double-strand break repair …
The use of tumor-treating fields (TTFields) has revolutionized the treatment of recurrent and
newly diagnosed glioblastoma (GBM). TTFields are low-intensity, intermediate frequency …
newly diagnosed glioblastoma (GBM). TTFields are low-intensity, intermediate frequency …
A review on tumor-treating fields (TTFields): clinical implications inferred from computational modeling
C Wenger, PC Miranda, R Salvador… - IEEE reviews in …, 2018 - ieeexplore.ieee.org
Tumor-treating fields (TTFields) are a cancer treatment modality that uses alternating electric
fields of intermediate frequency (~ 100-500 kHz) and low intensity (1-3 V/cm) to disrupt cell …
fields of intermediate frequency (~ 100-500 kHz) and low intensity (1-3 V/cm) to disrupt cell …
Permeabilizing cell membranes with electric fields
AA Aguilar, MC Ho, E Chang, KW Carlson, A Natarajan… - Cancers, 2021 - mdpi.com
Simple Summary The FDA recently approved a fourth approach (in addition to surgery,
radiation therapy, and chemotherapy) for treating glioblastoma; namely, tumor treating fields …
radiation therapy, and chemotherapy) for treating glioblastoma; namely, tumor treating fields …
Tumor Treating Fields (TTFields) concomitant with immune checkpoint inhibitors are therapeutically effective in non-small cell lung cancer (NSCLC) in vivo model
Tumor Treating Fields (TTFields) are electric fields that exert physical forces to disrupt
cellular processes critical for cancer cell viability and tumor progression. TTFields induce …
cellular processes critical for cancer cell viability and tumor progression. TTFields induce …
The schemes, mechanisms and molecular pathway changes of Tumor Treating Fields (TTFields) alone or in combination with radiotherapy and chemotherapy
G Tanzhu, L Chen, G Xiao, W Shi, H Peng… - Cell Death …, 2022 - nature.com
Abstract Tumor Treating Fields (TTFields) is a physical therapy that uses moderate
frequency (100–300 kHz) and low-intensity (1–3 V/cm) alternating electric fields to inhibit …
frequency (100–300 kHz) and low-intensity (1–3 V/cm) alternating electric fields to inhibit …
Tumour-treating fields (TTFields): Investigations on the mechanism of action by electromagnetic exposure of cells in telophase/cytokinesis
L Berkelmann, A Bader, S Meshksar, A Dierks… - Scientific reports, 2019 - nature.com
Tumour-treating fields (TTFields) use alternating electric fields which interfere with dividing
cells, thereby reducing tumour growth. Previous reports suggest that electrical forces on cell …
cells, thereby reducing tumour growth. Previous reports suggest that electrical forces on cell …
[HTML][HTML] Wild-type IDH2 promotes the Warburg effect and tumor growth through HIF1α in lung cancer
J Li, Y He, Z Tan, J Lu, L Li, X Song, F Shi, L Xie… - Theranostics, 2018 - ncbi.nlm.nih.gov
Hotspot mutations of isocitrate dehydrogenase 1 and 2 (IDH1/2) have been studied in
several cancers. However, the function of wild-type IDH2 in lung cancer and the mechanism …
several cancers. However, the function of wild-type IDH2 in lung cancer and the mechanism …