Tumor Treating Fields (TTFields) demonstrate antiviral functions in vitro, and safety for application to COVID-19 patients in a pilot clinical study

A Abutbul, H Mumblat, Y Porat, N Friedman… - Frontiers in …, 2023 - frontiersin.org
Coronaviruses are the causative agents of several recent outbreaks, including the COVID-
19 pandemic. One therapeutic approach is blocking viral binding to the host receptor. As …

Cost-effectiveness of tumor-treating fields plus standard therapy for advanced non-small cell lung cancer progressed after platinum-based therapy in the United States

W Tian, J Ning, L Chen, Y Zeng, Y Shi, G Xiao… - Frontiers in …, 2024 - frontiersin.org
Background: Tumor treating fields (TTF) was first approved for treatment of glioblastoma.
Recently, the LUNAR study demonstrated that TTF+ standard therapy (ST) extended survival …

[HTML][HTML] The therapeutic effects of tumor treating fields on cancer and noncancerous cells

EO Mahgoub, A Hussain, M Sharifi, M Falahati… - Arabian Journal of …, 2021 - Elsevier
Tumor treating fields (TTFields) are among clinically active anticancer modalities that utilize
low‐intensity, intermediate frequency (IF), and alternating electric fields (AEFs) to selectively …

[HTML][HTML] Tumor treating fields: An emerging treatment modality for thoracic and abdominal cavity cancers

TH Jones, JW Song, L Abushahin - Translational Oncology, 2022 - Elsevier
Tumor treating fields (TTFields)-an intermediate-frequency, electric field therapy-has
emerged as a promising alternative therapy for the treatment of solid cancers. Since the first …

Effects of tumor treating fields (TTFields) on human mesenchymal stromal cells

M Strack, J Kückelhaus, M Diebold, P Wuchter… - Journal of Neuro …, 2024 - Springer
Abstract Purpose Mesenchymal stromal cells (MSCs) within the glioblastoma
microenvironment have been shown to promote tumor progression. Tumor Treating Fields …

Molecular determinants of calcitriol signaling and sensitivity in glioma stem-like cells

S Rehbein, AL Possmayer, S Bozkurt, C Lotsch… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma is one of the worst cancer types and the most common
cancer originating within the brain. Patients afflicted by glioblastoma suffer from poor …

Direct‐Current Electric Field Distribution in the Brain for Tumor Treating Field Applications: A Simulation Study

YS Sun - Computational and mathematical methods in …, 2018 - Wiley Online Library
Tumor Treating Fields (TTFields) in combination with chemotherapy and/or radiotherapy
have been clinically reported to provide prolonged overall survival in glioblastoma patients …

Modelling tumor treating fields for the treatment of lung-based tumors

Z Bomzon, N Urman, C Wenger… - 2015 37th Annual …, 2015 - ieeexplore.ieee.org
Tumor Treating Fields (TTFields), low-intensity electric fields in the frequency range of 100-
500 kHz, exhibit antimitotic activity in cancer cells. TTFields were approved by the US Food …

Thermoplastic microfluidic bioreactors with integrated electrodes to study tumor treating fields on yeast cells

E Gencturk, KO Ulgen, S Mutlu - Biomicrofluidics, 2020 - pubs.aip.org
Tumor-treating fields (TTFields) are alternating electrical fields of intermediate frequency
and low intensity that can slow or inhibit tumor growth by disrupting mitosis division of …

The clinical application of tumor treating fields therapy in glioblastoma

MM Riley, P San, E Lok, KD Swanson… - JoVE (Journal of …, 2019 - jove.com
Glioblastoma is the most common and lethal form of brain cancer, with a median survival of
15 months after diagnosis and a 5 year survival rate of only 5% with current standard of care …