The non-essential amino acid cysteine is used within cells for multiple processes that rely on
the chemistry of its thiol group. Under physiological conditions, many non-transformed …

Living organisms are continuously exposed to xenobiotics. The major phase of enzymatic
detoxification in many species is the conjugation of activated xenobiotics to reduced …

Chapter 1: Introduction--Chapter 2: Integumentary System----Skin and subcutaneous tissue--
Chapter 3: Mammary Gland--Chapter 4: Haemopoietic and Lymphatic Systems …

We show that 7-glutamyl transpeptidase (GGT) is a glutathionase that enables cells to use
extracellular glutathione as a source of cysteine. We transfected NIH/3T3 mouse fibroblasts …

The mechanism of the elevation of serum γ‐glutamyl transpeptidase activity in cholestasis is
not clear. We therefore analyzed rat γ‐glutamyl transpeptidase activities in liver, bile and …

Abstract gamma-Glutamyl transpeptidase is a key enzyme in glutathione (GSH) salvage,
metabolism of endogenous mediators such as leukotrienes and prostaglandins …

Gamma-glutamyl transpeptidase (GGT) is an enzyme located at the external surface of
epithelial cells. It initiates extracellular glutathione (GSH) breakdown, provides cells with a …

Fatty liver is one of the most common and specific responses of the liver to injury.
Morphologists use this name to indicate a condition characterized by the appearance of …

Enzymes of glutathione metabolism, particularly gamma-glutamyltransferase (GGT) and
glutathione S-transferase (GST), play a role in multistage hepatocarcinogenesis. The …

Extracellular glutathione (GSH) is degraded by an external cell‐surface enzyme, γ‐
glutamyltranspeptidase (γ‐GT). The products are transported into cells to participate in …