Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

[HTML][HTML] The association of ACE1, ACE2, TMPRSS2, IFITM3 and VDR polymorphisms with COVID-19 severity: A systematic review and meta-analysis

Z Dobrijevic, D Robajac, N Gligorijevic, M Šunderic… - EXCLI …, 2022 - ncbi.nlm.nih.gov
Genes involved in the regulation of viral recognition and its entry into a host cell have been
identified as candidates for genetic association studies on COVID-19 severity. Published …

Effects of vitamin D receptor gene polymorphisms on the prognosis of COVID‐19

T Apaydin, H Polat, C Dincer Yazan, C Ilgin… - Clinical …, 2022 - Wiley Online Library
Purpose Vitamin D deficiency has emerged as another potential risk factor for coronavirus
disease (COVID‐19) due to the immunomodulatory effects of 25 hydroxyvitamin D [25 (OH) …

Vitamin D deficiency and vitamin D receptor FokI polymorphism as risk factors for COVID-19

NMS Zeidan, HMAE Lateef, DM Selim, SA Razek… - Pediatric …, 2023 - nature.com
Background Given the sparse data on vitamin D status in pediatric COVID-19, we
investigated whether vitamin D deficiency could be a risk factor for susceptibility to COVID …

Analysis of gene single nucleotide polymorphisms in COVID-19 disease highlighting the susceptibility and the severity towards the infection

MG Balzanelli, P Distratis, R Lazzaro, VH Pham… - Diagnostics, 2022 - mdpi.com
Many factors may influence the risk of being infected by SARS-CoV-2, the coronavirus
responsible for coronavirus disease 2019 (COVID-19). Exposure to the virus cannot explain …

Genetic variations of the vitamin D metabolic pathway and COVID-19 susceptibility and severity: current understanding and existing evidence

N Charoenngam, A Jaroenlapnopparat, SK Mettler… - Biomedicines, 2023 - mdpi.com
The immunomodulatory and metabolic effects of vitamin D receptor (VDR) activation have
been considered beneficial in mitigating the susceptibility and severity of COVID-19 …

Role of FokI rs2228570 and Tru9I rs757343 polymorphisms in the mortality of patients infected with different variants of SARS-CoV-2

HRS Shawi, E Anvari, A Fateh - Archives of Medical Research, 2023 - Elsevier
Background and aim Low vitamin D levels are associated with the severity of coronavirus
disease 19 (COVID-19). Vitamin D receptor gene polymorphisms, such as Tru9I rs757343 …

Association of ApaI rs7975232 and BsmI rs1544410 in clinical outcomes of COVID-19 patients according to different SARS-CoV-2 variants

ANR Al-Gharrawi, E Anvari, A Fateh - Scientific Reports, 2023 - nature.com
A growing body of research has shown how important vitamin D is in the prognosis of
coronavirus disease 19 (COVID-19). The vitamin D receptor is necessary for vitamin D to …

SARS-CoV-2 infection in multiple sclerosis patients: interaction with treatments, adjuvant therapies, and vaccines against COVID-19

A Muñoz-Jurado, BM Escribano, E Agüera… - Journal of …, 2022 - Springer
The SARS-CoV-2 pandemic has raised particular concern for people with Multiple Sclerosis,
as these people are believed to be at increased risk of infection, especially those being …

Vitamin D physiology, deficiency, genetic influence, and the effects of daily vs. bolus doses of vitamin D on overall health: a clinical approach

V Sorrenti, A Buriani, S Davinelli, G Scapagnini… - Nutraceuticals, 2023 - mdpi.com
Vitamin D is a pleiotropic hormone that plays a vital role in regulating bone growth,
maintaining calcium and phosphate homeostasis, modulating immune function, and a wide …