Asthma outcomes: biomarkers

SJ Szefler, S Wenzel, R Brown, SC Erzurum… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Measurement of biomarkers has been incorporated within clinical research
studies of asthma to characterize the population and associate the disease with …

Glucocorticoids for acute viral bronchiolitis in infants and young children

RM Fernandes, LM Bialy… - Cochrane Database …, 2010 - cochranelibrary.com
Background Previous systematic reviews have not shown clear benefit of glucocorticoids for
acute viral bronchiolitis, but their use remains considerable. Recent large trials add …

Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations

SJ Teach, MA Gill, A Togias, CA Sorkness… - Journal of Allergy and …, 2015 - Elsevier
Background Short-term targeted treatment can potentially prevent fall asthma exacerbations
while limiting therapy exposure. Objective We sought to compare (1) omalizumab with …

Inhaled corticosteroids in COPD and the risk of serious pneumonia

S Suissa, V Patenaude, F Lapi, P Ernst - Thorax, 2013 - thorax.bmj.com
Background Inhaled corticosteroids (ICS) are known to increase the risk of pneumonia in
patients with chronic obstructive pulmonary disease (COPD). It is unclear whether the risk of …

Inhaled corticosteroids and the risks of diabetes onset and progression

S Suissa, A Kezouh, P Ernst - The American journal of medicine, 2010 - Elsevier
BACKGROUND:: Systemic corticosteroids are known to increase diabetes risk, but the
effects of high-dose inhaled corticosteroids are unknown. We assessed whether the use and …

[HTML][HTML] Systemic side effects of inhaled corticosteroids in patients with asthma

R Dahl - Respiratory medicine, 2006 - Elsevier
Asthma is a complex disease of the respiratory tract associated with chronic inflammation in
which an intricate network of cells and cellular factors plays a major role. Asthma is one of …

Exhaled nitric oxide: a predictor of steroid response

AD Smith, JO Cowan, KP Brassett, S Filsell… - American journal of …, 2005 - atsjournals.org
Rationale: The initial management of patients who present with persistent respiratory
symptoms includes recognizing those with the potential to benefit from inhaled steroid …

Oral corticosteroids stewardship for asthma in adults and adolescents: a position paper from the Thoracic Society of Australia and New Zealand

J Blakey, LP Chung, VM McDonald, L Ruane… - …, 2021 - Wiley Online Library
Oral corticosteroids (OCS) are frequently used for asthma treatment. This medication is
highly effective for both acute and chronic diseases, but evidence indicates that …

Relevance of pharmacokinetics and pharmacodynamics of inhaled corticosteroids to asthma

H Derendorf, R Nave, A Drollmann… - European …, 2006 - Eur Respiratory Soc
The pharmacokinetic and pharmacodynamic effects of inhaled corticosteroids (ICS) have
shaped the efficacy and safety of these agents in the treatment of asthma. Important …

Glucocorticoid-induced osteoporosis: an update on effects and management

B Buehring, R Viswanathan, N Binkley… - Journal of allergy and …, 2013 - Elsevier
Glucocorticoids remain a cornerstone of guideline-based management of persistent asthma
and allergic diseases. Glucocorticoid-induced osteoporosis (GIO) is the most common …