Current status and future prospects in cannabinoid production through in vitro culture and synthetic biology

M Hesami, M Pepe, A Baiton, AMP Jones - Biotechnology Advances, 2023 - Elsevier
For centuries, cannabis has been a rich source of fibrous, pharmaceutical, and recreational
ingredients. Phytocannabinoids are the most important and well-known class of cannabis …

Decoding the Postulated Entourage Effect of Medicinal Cannabis: What It Is and What It Isn't

C Christensen, M Rose, C Cornett, M Allesø - Biomedicines, 2023 - mdpi.com
The 'entourage effect'term was originally coined in a pre-clinical study observing
endogenous bio-inactive metabolites potentiating the activity of a bioactive …

Cannabis constituents interact at the drug efflux pump BCRP to markedly increase plasma cannabidiolic acid concentrations

LL Anderson, MG Etchart, D Bahceci… - Scientific reports, 2021 - nature.com
Cannabis is a complex mixture of hundreds of bioactive molecules. This provides the
potential for pharmacological interactions between cannabis constituents, a phenomenon …

Translation of animal endocannabinoid models of PTSD mechanisms to humans: Where to next?

LJ Ney, KM Crombie, LM Mayo, KL Felmingham… - Neuroscience & …, 2022 - Elsevier
The endocannabinoid system is known to be involved in mechanisms relevant to PTSD
aetiology and maintenance, though this understanding is mostly based on animal models of …

Cannabinoid polymorphisms interact with plasma endocannabinoid levels to predict fear extinction learning

LJ Ney, A Matthews, CMK Hsu, DV Zuj… - Depression and …, 2021 - Wiley Online Library
Background The endocannabinoid system is gaining increasing attention as a favorable
target for improving posttraumatic stress disorder (PTSD) treatments. Exposure therapy is …

Therapeutic Potential of Minor Cannabinoids in Dermatological Diseases—A Synthetic Review

E Kwiecień, D Kowalczuk - Molecules, 2023 - mdpi.com
Dermatological diseases pose a significant burden on the quality of life of individuals and
can be challenging to treat effectively. In this aspect, cannabinoids are gaining increasing …

A Temporary Immersion System to Improve Cannabis sativa Micropropagation

S Rico, J Garrido, C Sánchez, C Ferreiro-Vera… - Frontiers in Plant …, 2022 - frontiersin.org
The aim of this study was to propagate axillary shoots of Cannabis sativa L. using liquid
medium in temporary immersion bioreactors. The effect of immersion frequency (3 or 6 …

Chloroform-based liquid-liquid extraction and LC–MS/MS quantification of endocannabinoids, cortisol and progesterone in human hair

LJ Ney, KL Felmingham, R Bruno, A Matthews… - … of pharmaceutical and …, 2021 - Elsevier
Understanding the role of endogenous cannabinoids (endocannabinoids) in disease is of
increasing importance. However, tools to investigate endocannabinoid levels in humans are …

Recent Research on Cannabis sativa L.: Phytochemistry, New Matrices, Cultivation Techniques, and Recent Updates on Its Brain-Related Effects (2018–2023)

L Siracusa, G Ruberto, L Cristino - Molecules, 2023 - mdpi.com
Cannabis sativa L. is a plant that humankind has been using for millennia. The basis of its
widespread utilization is its adaptability to so many different climatic conditions, with easy …

[HTML][HTML] Interpol Review of Drug Analysis 2019-2022

D Love, NS Jones - Forensic Science International: Synergy, 2023 - ncbi.nlm.nih.gov
Improved methods of analysis, ie, faster, more discriminatory, more sensitive, less costly,
etc., are needed for all abused substances. Additionally, standard analytical data are …