Advances in the development of cyclodextrin-based nanogels/microgels for biomedical applications: Drug delivery and beyond

F Topuz, T Uyar - Carbohydrate Polymers, 2022 - Elsevier
Nanogels/microgels are swollen cross-linked polymer networks with tunable
physicochemical properties and are commonly employed for the effective delivery of …

Cyclodextrin inclusion complexes for improved drug bioavailability and activity: synthetic and analytical aspects

Á Sarabia-Vallejo, MM Caja, AI Olives, MA Martín… - Pharmaceutics, 2023 - mdpi.com
Many active pharmaceutical ingredients show low oral bioavailability due to factors such as
poor solubility and physical and chemical instability. The formation of inclusion complexes …

Preparation, characterization, and physicochemical property of the inclusion complexes of Cannabisin A with β-cyclodextrin and hydroxypropyl-β-cyclodextrin

PW Xu, XF Yuan, H Li, Y Zhu, B Zhao - Journal of Molecular Structure, 2023 - Elsevier
Cannabisin A (CA), derived from hemp seed shells, has antioxidant and anti-
neuroinflammatory activity. However, its application is limited due to its poor solubility. In this …

Cyclodextrins for the delivery of Bioactive compounds from Natural sources: Medicinal, Food and cosmetics Applications

S Christaki, E Spanidi, E Panagiotidou… - Pharmaceuticals, 2023 - mdpi.com
Cyclodextrins have gained significant and established attention as versatile carriers for the
delivery of bioactive compounds derived from natural sources in various applications …

The design and discovery of topoisomerase I inhibitors as anticancer therapies

E Martín-Encinas, A Selas, F Palacios… - Expert Opinion on Drug …, 2022 - Taylor & Francis
Introduction Cancer has been identified as one of the leading causes of death worldwide.
The biological target of some anticancer agents is topoisomerase I, an enzyme involved in …

Recent advances in SN-38 drug delivery system

J Yang, L Jia, Z He, Y Wang - International Journal of Pharmaceutics, 2023 - Elsevier
DNA topoisomerase I plays a key role in lubricating the wheels of DNA replication or RNA
transcription through breaking and reconnecting DNA single-strand. It is widely known that …

Cyclodextrin and folate functionalized polymer nanocarriers: Chain length dependent properties

AS Pillai, A Alexander, GS Varalakshmi… - European Polymer …, 2022 - Elsevier
We report a series of β-cyclodextrin and folate-tethered poly (ethylene glycol) with various
spacer chain lengths, prepared and characterized using spectroscopic methods. The size …

Nanotechnology-Based Diagnostic and Therapeutic Strategies for Neuroblastoma

H Yan, B Zhai, F Yang, Z Chen, Q Zhou… - Frontiers in …, 2022 - frontiersin.org
Neuroblastoma (NB), as the most common extracranial solid tumor in childhood, is one of
the critical culprits affecting children's health. Given the heterogeneity and invisibility of NB …

Exploring the Potential of Nanogels: From Drug Carriers to Radiopharmaceutical Agents

M Kubeil, Y Suzuki, MA Casulli, R Kamal… - Advanced …, 2024 - Wiley Online Library
Nanogels open up access to a wide range of applications and offer among others hopeful
approaches for use in the field of biomedicine. This review provides a brief overview of …

Critical review in designing plant-based anticancer nanoparticles against hepatocellular carcinoma

A Basu, T Namporn, P Ruenraroengsak - Pharmaceutics, 2023 - mdpi.com
Hepatocellular carcinoma (HCC), accounting for 85% of liver cancer cases, continues to be
the third leading cause of cancer-related deaths worldwide. Although various forms of …