Quantitative gait and balance outcomes for ataxia trials: consensus recommendations by the ataxia global initiative working group on digital-motor biomarkers

W Ilg, S Milne, T Schmitz-Hübsch, L Alcock, L Beichert… - The Cerebellum, 2023 - Springer
With disease-modifying drugs on the horizon for degenerative ataxias, ecologically valid,
finely granulated, digital health measures are highly warranted to augment clinical and …

Gait analysis in neurorehabilitation: from research to clinical practice

M Bonanno, AM De Nunzio, A Quartarone, A Militi… - Bioengineering, 2023 - mdpi.com
When brain damage occurs, gait and balance are often impaired. Evaluation of the gait
cycle, therefore, has a pivotal role during the rehabilitation path of subjects who suffer from …

Human walking gait classification utilizing an artificial neural network for the ergonomics study of lower limb prosthetics

FT Putri, W Caesarendra, G Królczyk, A Glowacz… - Prosthesis, 2023 - mdpi.com
Prosthetics and orthotics research, studies, and technologies have been evolving through
the years. According to World Health Organization (WHO) data, it is estimated that, globally …

Pharmacological targeting of coagulation factor XI attenuates experimental autoimmune encephalomyelitis in mice

TCL Kohs, ME Fallon, EC Oseas, LD Healy… - Metabolic brain …, 2023 - Springer
Multiple sclerosis (MS) is the most common causes of non-traumatic disability in young
adults worldwide. MS pathophysiologies include the formation of inflammatory lesions …

Clinical Gait analysis: characterizing normal gait and pathological deviations due to neurological diseases

L Hermez, A Halimi, N Houmani, S Garcia-Salicetti… - Sensors, 2023 - mdpi.com
This study addresses the characterization of normal gait and pathological deviations
induced by neurological diseases, considering knee angular kinematics in the sagittal …

Clustering approaches for gait analysis within neurological disorders: a narrative review

J Hummel, M Schwenk, D Seebacher, P Barzyk… - Digital …, 2024 - karger.com
Background: The prevalence of neurological disorders is increasing, underscoring the
importance of objective gait analysis to help clinicians identify specific deficits. Nevertheless …

A Systematic Review of Gait Analysis in the Context of Multimodal Sensing Fusion and AI

R Katmah, A Al Shehhi, HF Jelinek… - … on Neural Systems …, 2023 - ieeexplore.ieee.org
Background: Neurological diseases are a leading cause of disability and mortality. Gait, or
human walking, is a significant predictor of quality of life, morbidity, and mortality. Gait …

Use of a Triaxial Accelerometer to Measure Changes in Gait Sway and Related Motor Function after Corrective Spinal Fusion Surgery for Adult Spinal Deformity

T Sakaguchi, N Sake, M Tanaka, Y Fujiwara… - Journal of Clinical …, 2024 - mdpi.com
Background: Adult spinal deformity is a complex condition that causes lower back pain,
causing spinal imbalance and discomfort in activities of daily life. After corrective spinal …

Monitoring Activity and Gait in Children (MAGIC) using digital health technologies

J Di, PG Tuttle, L Adamowicz, W Lin, H Zhang… - Pediatric …, 2024 - nature.com
Abstract Background Digital health technologies (DHTs) can collect gait and physical activity
in adults, but limited studies have validated these in children. This study compared gait and …

Measuring gait parameters from a single chest-worn accelerometer in healthy individuals: a validation study

N Camerlingo, X Cai, L Adamowicz, M Welbourn… - Scientific Reports, 2024 - nature.com
Digital health technologies (DHTs) are increasingly being adopted in clinical trials, as they
enable objective evaluations of health parameters in free-living environments. Although …