[HTML][HTML] Neutrophil Extracellular Traps Upregulate p21 and Suppress Cell Cycle Progression to Impair Endothelial Regeneration after Inflammatory Lung Injury

S Zhu, Y Yu, Q Hong, C Li, H Zhang, K Guo - Journal of Clinical Medicine, 2024 - mdpi.com
Background: Sepsis is a major cause of ICU admissions, with high mortality and morbidity.
The lungs are particularly vulnerable to infection and injury, and restoration of vascular …

YAP promotes endothelial barrier repair by repressing STAT3/VEGF signaling

X Fan, X Shan, S Jiang, S Wang, F Zhang, Q Tian… - Life Sciences, 2020 - Elsevier
Aims Endothelial barrier dysfunction is associated with multiple diseases, and barrier repair
may be a possible therapeutic target. Yes-associated protein and its pathway have been …

[HTML][HTML] Roles of Macrophages and Endothelial Cells and Their Crosstalk in Acute Lung Injury

S Osorio-Valencia, B Zhou - Biomedicines, 2024 - mdpi.com
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS),
present life-threatening conditions characterized by inflammation and endothelial injury …

[HTML][HTML] Genes in pediatric pulmonary arterial hypertension and the most promising BMPR2 gene therapy

L Dai, L Du - Frontiers in Genetics, 2022 - frontiersin.org
Pulmonary arterial hypertension (PAH) is a rare but progressive and lethal vascular disease
of diverse etiologies, mainly caused by proliferation of endothelial cells, smooth muscle cells …

Immunosuppression with Cyclosporine versus Tacrolimus shows distinctive nephrotoxicity profiles within renal compartments

H Demirci, S Popovic, C Dittmayer, DE Yilmaz… - Acta …, 2023 - Wiley Online Library
Abstract Aim Calcineurin inhibitors (CNIs) are the backbone for immunosuppression after
solid organ transplantation. Although successful in preventing kidney transplant rejection …

Fe 3+-catalyzed degradation of organic mercury as a simple post-column interface for the speciation of mercury by high-performance liquid chromatography-catalytic …

X Zhang, D Ji, Y Zhang, Y Lu, J Fu… - Journal of Analytical Atomic …, 2020 - pubs.rsc.org
A novel and simple interface used in a high-performance liquid chromatography-catalytic
cold vapor-atomic fluorescence spectrometry (HPLC-CCV-AFS) hyphenated system without …

Intercellular signaling dynamics from a single cell atlas of the biomaterials response

C Cherry, DR Maestas, J Han, JI Andorko, P Cahan… - BioRxiv, 2020 - biorxiv.org
Biomaterials serve as the basis of implants, tissue engineering scaffolds, and multiple other
biomedical therapeutics. New technologies, such as single cell RNA sequencing …

On the in vivo origin of human nasal mesenchymal stem cell cultures

R Choi, S Goncalves, MA Durante… - Laryngoscope …, 2020 - Wiley Online Library
Abstract Objectives Mesenchymal stem cells (MSCs), classically expanded in culture from
bone marrow, are of broad interest to the regenerative medicine community. Human nasal …

[HTML][HTML] Population-scale skeletal muscle single-nucleus multi-omic profiling reveals extensive context specific genetic regulation

A Varshney, N Manickam, P Orchard, A Tovar, Z Zhang… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Skeletal muscle, the largest human organ by weight, is relevant to several polygenic
metabolic traits and diseases including type 2 diabetes (T2D). Identifying genetic …

Seeing pulmonary hypertension through a paediatric lens: a viewpoint

S Agarwal, J Fineman, DN Cornfield… - European …, 2024 - Eur Respiratory Soc
Extract Pulmonary hypertension (PH) is a life-threating condition associated with abnormally
elevated pulmonary pressures and right heart failure. Current epidemiological data indicate …