[HTML][HTML] Neutrophil Extracellular Traps Upregulate p21 and Suppress Cell Cycle Progression to Impair Endothelial Regeneration after Inflammatory Lung Injury
S Zhu, Y Yu, Q Hong, C Li, H Zhang, K Guo - Journal of Clinical Medicine, 2024 - mdpi.com
Background: Sepsis is a major cause of ICU admissions, with high mortality and morbidity.
The lungs are particularly vulnerable to infection and injury, and restoration of vascular …
The lungs are particularly vulnerable to infection and injury, and restoration of vascular …
YAP promotes endothelial barrier repair by repressing STAT3/VEGF signaling
X Fan, X Shan, S Jiang, S Wang, F Zhang, Q Tian… - Life Sciences, 2020 - Elsevier
Aims Endothelial barrier dysfunction is associated with multiple diseases, and barrier repair
may be a possible therapeutic target. Yes-associated protein and its pathway have been …
may be a possible therapeutic target. Yes-associated protein and its pathway have been …
[HTML][HTML] Roles of Macrophages and Endothelial Cells and Their Crosstalk in Acute Lung Injury
S Osorio-Valencia, B Zhou - Biomedicines, 2024 - mdpi.com
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS),
present life-threatening conditions characterized by inflammation and endothelial injury …
present life-threatening conditions characterized by inflammation and endothelial injury …
[HTML][HTML] Genes in pediatric pulmonary arterial hypertension and the most promising BMPR2 gene therapy
L Dai, L Du - Frontiers in Genetics, 2022 - frontiersin.org
Pulmonary arterial hypertension (PAH) is a rare but progressive and lethal vascular disease
of diverse etiologies, mainly caused by proliferation of endothelial cells, smooth muscle cells …
of diverse etiologies, mainly caused by proliferation of endothelial cells, smooth muscle cells …
Immunosuppression with Cyclosporine versus Tacrolimus shows distinctive nephrotoxicity profiles within renal compartments
Abstract Aim Calcineurin inhibitors (CNIs) are the backbone for immunosuppression after
solid organ transplantation. Although successful in preventing kidney transplant rejection …
solid organ transplantation. Although successful in preventing kidney transplant rejection …
Fe 3+-catalyzed degradation of organic mercury as a simple post-column interface for the speciation of mercury by high-performance liquid chromatography-catalytic …
X Zhang, D Ji, Y Zhang, Y Lu, J Fu… - Journal of Analytical Atomic …, 2020 - pubs.rsc.org
A novel and simple interface used in a high-performance liquid chromatography-catalytic
cold vapor-atomic fluorescence spectrometry (HPLC-CCV-AFS) hyphenated system without …
cold vapor-atomic fluorescence spectrometry (HPLC-CCV-AFS) hyphenated system without …
Intercellular signaling dynamics from a single cell atlas of the biomaterials response
Biomaterials serve as the basis of implants, tissue engineering scaffolds, and multiple other
biomedical therapeutics. New technologies, such as single cell RNA sequencing …
biomedical therapeutics. New technologies, such as single cell RNA sequencing …
On the in vivo origin of human nasal mesenchymal stem cell cultures
Abstract Objectives Mesenchymal stem cells (MSCs), classically expanded in culture from
bone marrow, are of broad interest to the regenerative medicine community. Human nasal …
bone marrow, are of broad interest to the regenerative medicine community. Human nasal …
[HTML][HTML] Population-scale skeletal muscle single-nucleus multi-omic profiling reveals extensive context specific genetic regulation
Skeletal muscle, the largest human organ by weight, is relevant to several polygenic
metabolic traits and diseases including type 2 diabetes (T2D). Identifying genetic …
metabolic traits and diseases including type 2 diabetes (T2D). Identifying genetic …
Seeing pulmonary hypertension through a paediatric lens: a viewpoint
S Agarwal, J Fineman, DN Cornfield… - European …, 2024 - Eur Respiratory Soc
Extract Pulmonary hypertension (PH) is a life-threating condition associated with abnormally
elevated pulmonary pressures and right heart failure. Current epidemiological data indicate …
elevated pulmonary pressures and right heart failure. Current epidemiological data indicate …