[HTML][HTML] Exposure to endocrine disruptors during adulthood: consequences for female fertility

S Rattan, C Zhou, C Chiang… - Journal of …, 2017 - joe.bioscientifica.com
Endocrine disrupting chemicals are ubiquitous chemicals that exhibit endocrine disrupting
properties in both humans and animals. Female reproduction is an important process, which …

Metabolic regulation is important for spermatogenesis

L Rato, MG Alves, S Socorro, AI Duarte… - Nature Reviews …, 2012 - nature.com
Male factor infertility is increasing in developed countries, and several factors linked to
lifestyle have been shown to negatively affect spermatogenesis. Sertoli cells are pivotal to …

[HTML][HTML] Steroidogenesis in Leydig cells: effects of aging and environmental factors

Y Wang, F Chen, L Ye, B Zirkin, H Chen - Reproduction, 2017 - rep.bioscientifica.com
Serum testosterone (TS) levels decrease with aging in both humans and rodents. Using the
rat as a model system, it was found that age-related reductions in serum TS were not due to …

Reproductive toxic potential of phthalate compounds–State of art review

S Sedha, H Lee, S Singh, S Kumar, S Jain… - Pharmacological …, 2021 - Elsevier
Phthalates are pervasive compounds, and due to the ubiquitous usage of phthalates,
humans or even children are widely exposed to them. Since phthalates are not chemically …

The impact of sperm DNA damage in assisted conception and beyond: recent advances in diagnosis and treatment

SEM Lewis, RJ Aitken, SJ Conner, G De Iuliis… - Reproductive …, 2013 - Elsevier
Sperm DNA damage is a useful biomarker for male infertility diagnosis and prediction of
assisted reproduction outcomes. It is associated with reduced fertilization rates, embryo …

Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion

L Zeng, J Zhou, X Wang, Y Zhang, M Wang… - Free Radical Biology and …, 2021 - Elsevier
Ferroptosis is a newly defined programmed cell death pathway characterized by iron
overload and lipid peroxidation. Increasing studies show that autophagy regulates …

[HTML][HTML] Intracytoplasmic sperm injection: state of the art in humans

GD Palermo, CL O'neill, S Chow, S Cheung… - …, 2017 - rep.bioscientifica.com
Among infertile couples, 25% involve both male and female factors, while male factor alone
accounts for another 25% due to oligo-, astheno-, teratozoospermia, a combination of the …

Insecticide imidacloprid induces morphological and DNA damage through oxidative toxicity on the reproductive organs of developing male rats

R Bal, M Naziroğlu, G Türk, Ö Yilmaz… - Cell biochemistry …, 2012 - Wiley Online Library
We investigated whether treatment with imidacloprid would induce morphological changes,
DNA fragmentation, antioxidant imbalance and apoptosis in the reproductive system of …

[HTML][HTML] DEHP exposure destroys blood-testis barrier (BTB) integrity of immature testes through excessive ROS-mediated autophagy

WEI Yi, T Xiang-Liang, Z Yu, L Bin, S Lian-Ju… - Genes & diseases, 2018 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP), is known to impair testicular functions and
reproduction. However, its effects on immature testis Blood-testis barrier (BTB) and the …

[HTML][HTML] Genetic and epigenetic alterations induced by bisphenol A exposure during different periods of spermatogenesis: from spermatozoa to the progeny

M Lombó, C Fernández-Díez, S González-Rojo… - Scientific Reports, 2019 - nature.com
Exposure to bisphenol A (BPA) has been related to male reproductive disorders. Since this
endocrine disruptor also displays genotoxic and epigenotoxic effects, it likely alters the …