In the last two decades, there has been a growing interest in unraveling the role that the
Na+/Ca2+ exchanger (NCX) plays in the function and regulation of several cellular activities …

Although K+ channels activated by Ca 2+ have long been known to shape neuronal
excitability, evidence is accumulating that K+ channels sensitive to intracellular Na+, termed …

The Slack and Slick genes encode potassium channels that are very widely expressed in
the central nervous system. These channels are activated by elevations in intracellular …

Developmental and epileptic encephalopathies (DEEs) are severe seizure disorders with
inadequate treatment options. Gain-or loss-of-function mutations of neuronal ion channel …

The Na+/Ca2+ exchanger (NCX) is a bidirectional transporter that normally extrudes Ca2+
from the cell (forward mode), but also brings Ca2+ into the cell (reverse mode) under special …

The Slack (Sequence like a calcium-activated K channel)(Slo2. 2) gene is abundantly
expressed in the mammalian brain and encodes a sodium-activated K+ (KNa) channel …

Mitochondria play an important role in tissue ischemia and reperfusion (IR) injury, with
energetic failure and the opening of the mitochondrial permeability transition pore being the …

Using the whole-cell voltage clamp, we examined acute effects of various agents on Na+/Ca
2+ exchange current (I NCX) in guinea-pig cardiac ventricular cells and transfected cells …

We investigated the effects of bepridil on the two components of the delayed rectifier K+
current, ie, the rapidly activating (IKr) and the slowly activating (IKs) currents using tight‐seal …

Ample evidence supports the theory that trabecular meshwork possesses smooth-muscle-
like properties. Trabecular meshwork cells express a large number of transporters, channels …