[HTML][HTML] Research progress in the molecular mechanisms, therapeutic targets, and drug development of idiopathic pulmonary fibrosis

H Ma, X Wu, Y Li, Y Xia - Frontiers in Pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Recent studies have
identified the key role of crosstalk between dysregulated epithelial cells, mesenchymal …

Gut‐Lung microbiota in chronic pulmonary diseases: evolution, pathogenesis, and therapeutics

CY Shi, CH Yu, WY Yu, HZ Ying - Canadian Journal of …, 2021 - Wiley Online Library
The microbiota colonized in the human body has a symbiotic relationship with human body
and forms a different microecosystem, which affects human immunity, metabolism …

Lung microbiota contribute to pulmonary inflammation and disease progression in pulmonary fibrosis

DN O'Dwyer, SL Ashley, SJ Gurczynski… - American journal of …, 2019 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) causes considerable global morbidity and
mortality, and its mechanisms of disease progression are poorly understood. Recent …

An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management

G Raghu, HR Collard, JJ Egan, FJ Martinez… - American journal of …, 2011 - atsjournals.org
This document is an international evidence-based guideline on the diagnosis and
management of idiopathic pulmonary fibrosis, and is a collaborative effort of the American …

[HTML][HTML] Regulation of immune function by the lymphatic system in lymphedema

RP Kataru, JE Baik, HJ Park, I Wiser, S Rehal… - Frontiers in …, 2019 - frontiersin.org
The lymphatic vasculature has traditionally been thought to play a passive role in the
regulation of immune responses by transporting antigen presenting cells and soluble …

Smoking and idiopathic pulmonary fibrosis

CK Oh, LA Murray, NA Molfino - Pulmonary medicine, 2012 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF) is a disease of unknown etiology with considerable
morbidity and mortality. Cigarette smoking is one of the most recognized risk factors for …

The role of immune response in the pathogenesis of idiopathic pulmonary fibrosis: far beyond the Th1/Th2 imbalance

P Spagnolo, R Tonelli, AV Samarelli… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic disease of unknown origin
characterized by progressive scarring of the lung leading to irreversible loss of function …

[HTML][HTML] IL-13Rα2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice

MS Wilson, E Elnekave… - The Journal of …, 2007 - Am Soc Clin Investig
Development of persistent Th2 responses in asthma and chronic helminth infections are a
major health concern. IL-10 has been identified as a critical regulator of Th2 immunity, but …

Multiplatform single-cell analysis identifies immune cell types enhanced in pulmonary fibrosis

APM Serezani, BD Pascoalino… - American Journal of …, 2022 - atsjournals.org
Immune cells have been implicated in idiopathic pulmonary fibrosis (IPF), but the
phenotypes and effector mechanisms of these cells remain incompletely characterized. We …

[HTML][HTML] S2K-Leitlinie zur Diagnostik und Therapie der idiopathischen Lungenfibrose

J Behr, A Günther, W Ammenwerth, I Bittmann… - …, 2013 - thieme-connect.com
Die idiopathische pulmonale Fibrose (IPF) ist eine schwerwiegende und in der Regel zum
Tod führende Erkrankung, die bisher nur unzureichend behandelt werden kann …