[HTML][HTML] The functions of SET domain bifurcated histone lysine methyltransferase 1 (SETDB1) in biological process and disease

H Luo, X Wu, XH Zhu, X Yi, D Du, DS Jiang - Epigenetics & Chromatin, 2023 - Springer
Histone methyltransferase SETDB1 (SET domain bifurcated histone lysine
methyltransferase 1, also known as ESET or KMT1E) is known to be involved in the …

Unlocking the potential of histone modification in regulating bone metabolism

J Zhang, H Liu, Y Liu, E Luo, S Liu - Biochimie, 2024 - Elsevier
Bone metabolism plays a crucial role in maintaining normal bone tissue homeostasis and
function. Imbalances between bone formation and resorption can lead to osteoporosis …

[HTML][HTML] SETDB1 regulates short interspersed nuclear elements and chromatin loop organization in mouse neural precursor cells

D Sun, Y Zhu, W Peng, S Zheng, J Weng, S Dong, J Li… - Genome Biology, 2024 - Springer
Background Transposable elements play a critical role in maintaining genome architecture
during neurodevelopment. Short Interspersed Nuclear Elements (SINEs), a major subtype of …

[HTML][HTML] Atf7ip Inhibits Osteoblast Differentiation via Negative Regulation of the Sp7 Transcription Factor

G Hu, X Shi, X Qu, C Han, A Hu, Z Jia, J Yang… - International Journal of …, 2023 - mdpi.com
Epigenetic modifications are critical for cell differentiation and growth. As a regulator of
H3K9 methylation, Setdb1 is implicated in osteoblast proliferation and differentiation. The …

[HTML][HTML] Histone methyltransferase Setdb1 mediates osteogenic differentiation by suppressing the expression of miR-212-3p under mechanical unloading

L Zhang, L Xu, Y Wang, X Zhang, T Xue, Q Sun… - Cellular …, 2023 - Elsevier
Emerging evidence indicates that multiple mechanisms are involved in bone loss induced
by mechanical unloading. Thus far, few study has established the pathophysiological role of …

[HTML][HTML] Melatonin Regulates Osteoblast Differentiation through the m6A Reader hnRNPA2B1 under Simulated Microgravity

Q Sun, L Xu, Z Hu, J Liu, T Yu, M Li, S Zhang… - Current Issues in …, 2024 - mdpi.com
Recent studies have confirmed that melatonin and N6-methyladenosine (m6A) modification
can influence bone cell differentiation and bone formation. Melatonin can also regulate a …

Role of epigenetic regulatory mechanisms in age‐related bone homeostasis imbalance

Y Zhong, X Zhou, Z Pan, J Zhang, J Pan - The FASEB Journal, 2024 - Wiley Online Library
Alterations to the human organism that are brought about by aging are comprehensive and
detrimental. Of these, an imbalance in bone homeostasis is a major outward manifestation of …

Atf7ip 是骨形态发生蛋白2 促小鼠胚胎成体细胞成骨分化的负调节因子

石现, 韩淳青, 胡安然, 况舒韵, 冉依梦, 吴郁 - 中国组织工程研究, 2024 - cjter.com
Atf7ip 是骨形态发生蛋白2 促小鼠胚胎成体细胞成骨分化的负调节因子 Page 1 Chinese Journal of
Tissue Engineering Research|Vol 28|No.31|November 2024|4931 中国组织工程研究 Chinese …

Atf7ip is a negative regulator of bone morphogenetic protein 2 promoting osteogenic differentiation in mouse embryonic adult cells

X Shi, C Han, A Hu, S Kuang, Y Ran, Y Wu - Chinese Journal of Tissue …, 2024 - cjter.com
BACKGROUND: Whether activating transcription factor 7 interacting protein (Atf7ip) is
involved in the regulation in osteogenic differentiation is still controversial, and studying its …