The number of lipophilic drug candidates in pharmaceutical discovery pipelines has
increased in recent years. These drugs often possess physicochemical properties that result …

Targeted drug delivery is constantly updated with a better understanding of the physiological
and pathological features of various diseases. Depending on high safety, good compliance …

Micro-and nano-scale particulate formulations are widely investigated towards improving the
oral bioavailability of both biologics and drugs with low solubility and/or low intestinal …

Efforts in discovering new and effective neurotherapeutics are made daily, although most fail
to reach clinical trials. The main reason is their poor bioavailability, related to poor aqueous …

Inflammatory bowel disease (IBD) is a serious chronic intestinal disorder with an increasing
global incidence. However, current treatment strategies, such as anti-inflammatory drugs …

Oral chemotherapy can improve the life quality of patients; however, the therapeutic effects
are limited by low bioavailability and rapid in vivo elimination of anticancer drugs. Here, we …

The role of advanced drug delivery strategies in drug repositioning and minimizing drug
attrition rates, when applied early in drug discovery, is poised to increase the translational …

Drug delivery systems (DDS) control the amount, rate, and site of administration of drug
substances in the body as well as their release and ADME (absorption, distribution …

Abstract Background Micro-and nanoplastics (MNPs) represent one of the most widespread
environmental pollutants of the twenty-first century to which all humans are orally exposed …

Background Oral chemotherapy is preferred for patients with cancer owing to its multiple
advantages, including convenience, better patient compliance, and improved safety …