Nanoparticles (NPs) have been widely used in different areas, including consumer products
and medicine. In terms of biomedical applications, NPs or NP-based drug formulations have …

Nucleic acid (NA) therapy has gained importance over the past decade due to its high
degree of selectivity and minimal toxic effects over conventional drugs. Currently …

The oral route of administration for lipid-based nanocarriers is of immense importance for
the drugs having low bioavailability because of extensive first-pass metabolism. These drug …

Background: Combination antiretroviral therapy has significantly advanced HIV-1 infection
treatment. However, HIV-1 remains persistent in the brain; the inaccessibility of the blood …

Inspired by the unique pharmacological effects of chiral drugs in the asymmetrical body
environments, it is assumed that the chirality of nanocarriers is also a key factor to determine …

Mucosal vaccines that stimulate both mucosal and systemic immune responses are
desirable, as they could prevent the invading pathogens at their initial infection sites in a …

Verapamil, a calcium channel blocker has poor bioavailability (20–30%) owing to extensive
hepatic first-pass metabolism. Hence, the major objective of this research was to improve the …

The use of nanoparticles (NPs) has surely grown in recent years due to their versatility, with
a spectrum of applications that range from nanomedicine to the food industry. Recent …

Breast cancer represents a lifethreatening problem globally. The major challenge in the
clinical setting is the management of cancer resistance and metastasis. Hybrid therapy can …

In dosage form design, drug delivery technology facing a major problem due to degradation
of the drug through the first-pass metabolism upon oral delivery. We can overcome this …