Unveiling the role of nonionic surfactants in enhancing cefotaxime drug solubility: a UV-Visible spectroscopic investigation in single and mixed micellar formulations
This study reports the interfacial phenomenon of cefotaxime in combination with nonionic
surfactants, Triton X-100 (TX-100) and Tween-80 (TW-80), and their mixed micellar …
surfactants, Triton X-100 (TX-100) and Tween-80 (TW-80), and their mixed micellar …
Oral Multidrug CoDelivery System Targeting Differential Sites for Diabetes Mellitus Treatment
H Zhang, R Wang, Z Xu, S Deng… - Advanced Functional …, 2024 - Wiley Online Library
Although regulation of the blood glucose level is a common therapy for Type 2 diabetes
mellitus (T2DM), the root cause of this disease (such as the damage of pancreatic β cells) …
mellitus (T2DM), the root cause of this disease (such as the damage of pancreatic β cells) …
[HTML][HTML] Vegetable oils composition affects the intestinal lymphatic transport and systemic bioavailability of co-administered lipophilic drug cannabidiol
W Feng, C Qin, S Abdelrazig, Z Bai, M Raji… - International journal of …, 2022 - Elsevier
Although natural sesame oil has been shown to facilitate the lymphatic delivery and oral
bioavailability of the highly lipophilic drug cannabidiol (CBD), considerable variability …
bioavailability of the highly lipophilic drug cannabidiol (CBD), considerable variability …
The emerging roles of long noncoding RNAs in lymphatic vascular development and disease
KI Ivanov, OV Samuilova, AA Zamyatnin Jr - Cellular and Molecular Life …, 2023 - Springer
Recent advances in RNA sequencing technologies helped uncover what was once
uncharted territory in the human genome—the complex and versatile world of long …
uncharted territory in the human genome—the complex and versatile world of long …
Developments and challenges for new and emergent preparations for male hypogonadism treatment
Introduction The specific role of testosterone (T) replacement therapy in patients with late
onset hypogonadism is still conflicting. Several available preparations have been developed …
onset hypogonadism is still conflicting. Several available preparations have been developed …
Quality by design (QbD) commended exploration of bosutinib loaded lipid nanocarriers for food effect attenuation and bioavailability enhancement in breast cancer
Bosutinib (BOS), a BCS class IV drug suffers from poor aqueous solubility and bioavailability
along with significant food effect. Lipid nanocarriers (LNC) have the potential to circumvent …
along with significant food effect. Lipid nanocarriers (LNC) have the potential to circumvent …
The role of nanocarriers for transdermal application targeted to lymphatic drug delivery: Opportunities and challenges
TC De Oliveira, MEV Tavares… - Journal of Drug Delivery …, 2022 - Elsevier
The transdermal route is a promising drug delivery strategy as it is a non-invasive pathway. It
may provide a controlled drug release, with longer-lasting effects on the organism as it does …
may provide a controlled drug release, with longer-lasting effects on the organism as it does …
Recent advances in oral peptide or protein-based drug liposomes
J Cui, Z Wen, W Zhang, W Wu - Pharmaceuticals, 2022 - mdpi.com
The high physiology and low toxicity of therapeutic peptides and proteins have made them a
hot spot for drug development in recent years. However, their poor oral bioavailability and …
hot spot for drug development in recent years. However, their poor oral bioavailability and …
[HTML][HTML] Development and in vivo pharmacokinetic and pharmacodynamic evaluation of an oral innovative cyclodextrin complexed lipid nanoparticles of irbesartan …
N Dudhipala, S Ettireddy, AAA Youssef… - …, 2023 - ncbi.nlm.nih.gov
Background: Irbesartan (IR) is used in the treatment of hypertension, heart failure, and
nephropathy in Type II diabetes. IR bioavailability is limited by poor solubility and …
nephropathy in Type II diabetes. IR bioavailability is limited by poor solubility and …
The lymphatic system: A sometimes-forgotten compartment in pharmaceutical sciences
The uniqueness of structure and physiology of the lymphatic system make it challenging to
delineate all its contributions in the maintenance of our health. However, in the past two …
delineate all its contributions in the maintenance of our health. However, in the past two …