The lymphatic system (LS) plays a crucial role in fluid balance, transportation of
macromolecules, and immune response. Moreover, LS is a channel for microbial invasion …

The lymphatic system plays a crucial role in the absorption of lipophilic drugs, making it an
important route for drug delivery. In this study, an in vitro model using Intralipid® was …

Recently, the intestinal lymphatic transport based on Peyer's patches (PPs) is emerging as a
promising absorption pathway for natural polysaccharides. Herein, the aim of this study is to …

The oral route is most favorable for drug delivery because of easy manufacturing and
handling, less strict regulatory requirements, fewer safety concerns and high patient …

As an essential branch of targeted drug delivery, oral targeted delivery is attracting growing
attention in recent years. In addition to site-specific delivery for the treatment of locoregional …

Oral peptide delivery is trending again. Among the possible reasons are the recent
approvals of two oral peptide formulations, which represent a huge stride in the field. For the …

As a recently discovered waste removal system in the brain, cerebral lymphatic system is
thought to play an important role in regulating the homeostasis of the central nervous …

Introduction Oral administration of cannabinoids is a convenient route of administration in
many cases. To enhance the poor and variable bioavailability of cannabinoids, selected …

In the harsh gastrointestinal tract, helical bacteria with hierarchical chiral architectures
possess strong abilities. Taking inspirations from nature, we developed a multichiral …

Oral delivery is the most widely used modality for drug administration, but its efficiency is
hampered by the limited drug absorption in the gastrointestinal tract. To address this issue …