Effective in vivo reactivation of HIV-1 latency reservoir via oral administration of EK-16A-SNEDDS
J Yang, C Shi, Y Cheng, Y Zhu, X Yang, Y Liang… - European Journal of …, 2024 - Elsevier
The latent reservoir of human immunodeficiency virus (HIV) is a major obstacle in the
treatment of acquired immune deficiency syndrome (AIDS). The “shock and kill” strategy has …
treatment of acquired immune deficiency syndrome (AIDS). The “shock and kill” strategy has …
Vesicular drug delivery systems for oral absorption enhancement
L Zou, M Cheng, K Hu, J Feng, L Tu - Chinese Chemical Letters, 2024 - Elsevier
Oral administration is the most acceptable route of drug delivery at this stage due to its
convenience, safety, and non-invasiveness. However, drugs given orally are exposed to a …
convenience, safety, and non-invasiveness. However, drugs given orally are exposed to a …
[HTML][HTML] Preparation and evaluation of antidiabetic activity of mangiferin-loaded solid lipid nanoparticles
This study aimed to develop and optimize mangiferin-loaded solid lipid nanoparticles (MG-
SLNs) using the microemulsion technique and ultrasonication. The MG-SLNs were …
SLNs) using the microemulsion technique and ultrasonication. The MG-SLNs were …
Formation mechanism of herpetrione self-assembled nanoparticles based on pH-driven method
Y Zhu, X Deng, Y Wu, B Shen, L Hang, Y Xue… - Chinese Chemical …, 2024 - Elsevier
The self-assembled nanoparticles (SAN) formed during the decoction process of traditional
Chinese medicine (TCM) exhibit non-uniform particle sizes and a tendency for aggregation …
Chinese medicine (TCM) exhibit non-uniform particle sizes and a tendency for aggregation …
Hydroxymethylnitrofurazone lymphatic uptake with nanostructured lipid carrier after oral administration in rats
Background: Leishmaniasis, caused by the protozoan Leishmania sp., infects phagocyte
cells present in lymphatic organs. This study demonstrates the influence of nanostructured …
cells present in lymphatic organs. This study demonstrates the influence of nanostructured …
Research Advances of Lipid Nanoparticles in the Treatment of Colorectal Cancer
J Zhang, K Ali, J Wang - International Journal of Nanomedicine, 2024 - Taylor & Francis
Colorectal cancer (CRC) is a common type of gastrointestinal tract (GIT) cancer and poses
an enormous threat to human health. Current strategies for metastatic colorectal cancer …
an enormous threat to human health. Current strategies for metastatic colorectal cancer …
Ex vivo fluorescence imaging for the identification of rhodaminelabeled bovine serum albumin and chitosancoated gold and silver nanoparticles
M Devanabanda, SS Sana, R Vadde… - Journal of …, 2023 - Wiley Online Library
Therapeutic potential and toxic effects of in vivo administered gold nanoparticles (GNPs)
and silver nanoparticles (SNP) depend on distribution in tissues. Rhodamine (Rho) labeled …
and silver nanoparticles (SNP) depend on distribution in tissues. Rhodamine (Rho) labeled …
[HTML][HTML] Immune-awakening Saccharomyces-inspired nanocarrier for oral target delivery to lymph and tumors
Y Mao, X Wang, C Chen, Q Zhao, Y Liu, J Zhang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Utilization of the intestinal lymphatic pathway will allow extraordinary gains in lymph and
tumors cascade-targeted delivery of oral drugs and awakening the innate/adaptive immunity …
tumors cascade-targeted delivery of oral drugs and awakening the innate/adaptive immunity …
Nanoemulsion Improves the Anti-Inflammatory Effect of Intraperitoneal and Oral Administration of Carvacryl Acetate
RL Souza, LCF Opretzka, MC Morais, CO Melo… - Pharmaceuticals, 2023 - mdpi.com
Carvacryl acetate (CA) is a monoterpene obtained from carvacrol, which exhibits anti-
inflammatory activity. However, its low solubility in aqueous media limits its application and …
inflammatory activity. However, its low solubility in aqueous media limits its application and …
Lipid-based formulations: A promising approach for poorly soluble drug delivery via the intestinal lymphatic system
S Yan, Y Cheng, L Li, C Zhong, C Chen… - Journal of Drug Delivery …, 2023 - Elsevier
Lipid-based formulation (LBF) has attracted more and more attention as it can significantly
improve the efficiency of oral delivery of poorly soluble drugs by exploiting the specific …
improve the efficiency of oral delivery of poorly soluble drugs by exploiting the specific …