In Vitro Predictive Model for Intestinal Lymphatic Uptake: Exploration of Additional Enhancers and Inhibitors

M Yousef, C O'Croinin, TS Le, C Park, J Zuo… - Pharmaceutics, 2024 - mdpi.com
Drug absorption via chylomicrons holds significant implications for both pharmacokinetics
and pharmacodynamics. However, a mechanistic understanding of predicting in vivo …

Recent approaches to investigate drug delivery systems through the lymphatic pathway using oral lipid-based formulations

SJ Jeong, WY Song, CW Park, DW Kim - Journal of Pharmaceutical …, 2024 - Springer
Background Lymphatic oral drug delivery systems are considered optimal for enhancing oral
drug delivery. They offer the advantage of delivering drugs directly to the immune system …

In-silico screening of bioactive compounds from nut grass (Cyperus rotundus) to inhibit the α-bungarotoxin from Kraits (Bungarus spp.) venom

R Grahadi, MH Widyananda, S Rahayu… - Egyptian Journal of …, 2024 - Taylor & Francis
Kraits (Bungarus spp.) are the snakes that commonly cause fatal bites in Tropical Asia due
to their neurotoxic venom. The complex process of antivenom production contributes to the …

Could nanotechnology improve exercise performance? Evidence from animal studies

MR Lima, BJ Moreira, R Bertuzzi… - Brazilian Journal of …, 2024 - SciELO Brasil
This review provides the current state of knowledge regarding the use of nutritional
nanocompounds on exercise performance. The reviewed studies used the following …

Nicotinamide Mononucleotide Supplementation: Understanding Metabolic Variability and Clinical Implications

C Benjamin, R Crews - Metabolites, 2024 - mdpi.com
Recent years have seen a surge in research focused on NAD+ decline and potential
interventions, and despite significant progress, new discoveries continue to highlight the …

Tyloxapol and nanoliposomes induce selective delivery of 5fluorouracil into hepatic tissues via VLDL/LDLmediated pathway

GI Harisa, SA Alanazi, MM Badran… - European Journal of …, 2024 - Wiley Online Library
This study aimed to enhance the hepatic targeting of 5fluorouracil (5FU) by tyloxapol
(TYL) and nanoliposomes to promote drug efficacy and safety. The lipophilicity of 5FU was …

Application of solid lipid nanoparticles preparation in infection caused by antibiotic-resistant bacteria

N Prastiwi, K Lesbatta - Indonesian Journal of Pharmacology …, 2021 - journal.ugm.ac.id
Solid lipid nanoparticles (SLN) is a potential alternative method for drug delivery due to its
good stability, low toxicity, can be modified and controlled in drug release, as well as can be …

Construction and antitumor effect of yeast microencapsulated nano-zinc oxide drug delivery system

Z Li, J Li, D Wang, C Li, K Zhang, L Wang… - Journal of Drug Delivery …, 2024 - Elsevier
In order to construct an oral drug delivery system to improve the bioavailability of drugs. This
project prepared a compound drug carrier that combines the advantages of biological …

Colitis and colorectal carcinogenesis: the focus on isolated lymphoid follicles

G Műzes, B Bohusné Barta, F Sipos - Biomedicines, 2022 - mdpi.com
Gut-associated lymphoid tissue is one of the most diverse and complex immune
compartments in the human body. The subepithelial compartment of the gut consists of …

[HTML][HTML] Transepithelial transport of nanoparticles in oral drug delivery: From the perspective of surface and holistic property modulation

Y Zheng, S Luo, M Xu, Q He, J Xie, J Wu… - … Pharmaceutica Sinica B, 2024 - Elsevier
Despite the promising prospects of nanoparticles in oral drug delivery, the process of oral
administration involves a complex transportation pathway that includes cellular uptake …