[PDF][PDF] In-Vivo Pharmacokinetics Study of Exemestane Hydrochloride Self-nanoemulsifying Drug Delivery Systems via Oral Route

BG Prajapati, B Prajapati, D Khunt - 2022 - researchgate.net
Exemestane HCl (EXM) is a novel irreversible steroidal aromatase inhibitor for the adjuvant
treatment of hormonally responsive breast cancer in postmenopausal women. Poor …

InflammationActivated Endogenous MacrophageMediated Prodrug Delivery System Overcoming Biological Barriers for Enhanced Oral Meningitis Therapy

VK Nguyen, N Nguyen, ZC Li, CM Cheng… - Advanced Functional … - Wiley Online Library
Significant health risks are posed by meningitis due to its rapid progression, and challenges
are encountered in intravenous antibiotic administration, especially in crossing the blood …

Lipoproteins within the lymphatic system: Insights into health, disease, and therapeutic implications

M Yousef, NB Chacra… - Applied …, 2023 - systems.enpress-publisher.com
This analysis of contemporary findings aims to enhance our understanding of lipoprotein
biology within the lymphatic system and its relevance to human health and disease. It delves …

Editorial of Special Issue of Hot Topic Reviews in Drug Delivery

Y Lv, W He, W Wu - Acta Pharmaceutica Sinica. B, 2021 - ncbi.nlm.nih.gov
Research in the cross-disciplines of drug delivery is developing at an accelerated speed
never seen before, as witnessed by the soaring number of yearly publications. A quick …

Nanoengineering/technology for diagnosis and treatment of ophthalmic diseases

R Sadasivam, M Goswami - Emerging Nanotechnologies for Medical …, 2023 - Elsevier
Early diagnosis of several ophthalmic diseases such as retinopathy, retinitis, conjunctivitis,
uveitis, etc., are challenging to clinicians. Prediction of ophthalmic diseases in their early …

Oral lipid-based drug delivery approaches to improve the intestinal lymphatic transport and systemic bioavailability of a highly lipophilic drug cannabidiol

W Feng - 2022 - eprints.nottingham.ac.uk
Lipid-based formulations play a significant role in oral delivery of lipophilic drugs. Previous
studies have shown that natural sesame oil promotes the intestinal lymphatic transport and …

Preparation and evaluation of novel self-dispersing lipid formulation of nevirapine for oral delivery

GB Preethi, HN Shivakumar… - Journal of Applied …, 2022 - japsonline.com
Nevirapine, a non-nucleoside reverse transcriptase inhibitor, exhibits pH-dependent
solubility resulting in poor dissolution limiting its absorption. In the present study, an attempt …

Targeted bio-distribution of drugs to the lymphatic system

A Jewell - 2022 - eprints.nottingham.ac.uk
Targeted drug delivery to the intestinal lymphatic system has emerged as an important goal
in drug development for the treatment of a number of clinical indications. These include …

MECHANISTIC OUTCOMES OF LIPID CORE ON SOLID LIPID NANOPARTICLE CHARACTERIZATION.

JB Chacko, GR Vijayasankar… - Indian …, 2024 - search.ebscohost.com
In our present study, solid lipid nanoparticles were fabricated by modified double
emulsification followed by ultracentrifugation method. The SLNs of the anti-HIV drugs …

Mesenteric Lymphatic Targeting of Antiretroviral agents for Improved Treatment of HIV/AIDS

YJ Chu - eprints.nottingham.ac.uk
Human immunodeficiency virus (HIV) is a worldwide pandemic that causes irreversible and
unstoppable disease progression. Antiretroviral therapy (ART) can efficiently suppress viral …