From transcription to translation, mRNA is complexed with heterogeneous nuclear
ribonucleoproteins (hnRNP proteins) that mediate mRNA processing, export from the …

Removal of introns from pre-mRNAs is an essential step in eukaryotic gene expression,
mediated by spliceosomes that contain snRNAs as key components. Although snRNAs are …

Mex67p is essential for nuclear poly (A)+ RNA export in yeast, but which specific transcripts
are transported by Mex67p is not known. We observed that thermosensitive mex67-5 cells …

Important progress in understanding messenger RNA export from the nucleus could be
achieved by increasing the list of proteins that are involved in this process. Here, we present …

The transport and localization of mRNAs results in the asymmetric synthesis of specific
proteins. In yeast, the nucleocytoplasmic shuttling protein She2 binds the ASH1 mRNA and …

Cold‐inducible RNA‐binding protein (CIRP) was originally found in mammalian cells as a
protein that is overexpressed upon a temperature downshift. Recently, we identified a …

The heterogeneous nuclear ribonucleoprotein Npl3p of budding yeast is a substrate of
arginine methyltransferase Hmt1p, but the role of Hmt1p in regulating Npl3p's functions in …

Abstract Background The Mitotic Exit Network (MEN) proteins–including the protein kinase
Cdc15 and the protein phosphatase Cdc14–are essential for exit from mitosis in …

Here, we develop computational methods to assess and consolidate large, diverse protein
interaction data sets, with the objective of identifying proteins involved in the coupling of …

The nuclear pore is a large and complex biological machine, mediating all signal‐directed
transport between the nucleus and the cytoplasm. The vertebrate pore has a mass of∼ 120 …