[HTML][HTML] Antibiotic-driven gut microbiome disorder alters the effects of sinomenine on morphine-dependent zebrafish

Z Chen, C Zhijie, Z Yuting, X Shilin, Z Qichun… - Frontiers in …, 2020 - frontiersin.org
Morphine is one of the most severely abused drugs in the world. Previous research on
morphine addiction has focused on the central nervous system (CNS). Studies have shown …

Concentrations of MDPV in rat striatum correlate with the psychostimulant effect

J Novellas, R López-Arnau, M Carbó… - Journal of …, 2015 - journals.sagepub.com
3, 4-methylenedioxypyrovalerone or MDPV is a synthetic cathinone with psychostimulant
properties more potent than cocaine. We quantified this drug in the striatum after …

Substances of abuse and the blood brain barrier: Interactions with physical exercise

MA Małkiewicz, A Małecki, M Toborek… - Neuroscience & …, 2020 - Elsevier
Substance use disorders pose a common medical, social and financial problem. Among the
pathomechanisms of substance use disorders, the disruption and increased permeability of …

Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures

S Baptista, AR Bento, J Gonçalves, L Bernardino… - …, 2012 - Elsevier
Methamphetamine (METH) is a psychostimulant drug of abuse that causes severe brain
damage. However, the mechanisms responsible for these effects are poorly understood …

Methamphetamine, 3, 4-methylenedioxymethamphetamine (MDMA) and 3, 4-methylenedioxypyrovalerone (MDPV) induce differential cytotoxic effects in bovine brain …

H Rosas-Hernandez, E Cuevas, SM Lantz, KC Rice… - Neuroscience …, 2016 - Elsevier
Designer drugs such as synthetic psychostimulants are indicative of a worldwide problem of
drug abuse and addiction. In addition to methamphetamine (METH), these drugs include 3 …

[HTML][HTML] The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties

TP Buzhdygan, CR Rodrigues, HM McGary… - Journal of …, 2021 - Springer
Background Synthetic cathinones are a category of psychostimulants belonging to the
growing number of designer drugs also known as “Novel Psychoactive Substances”(NPS) …

Peripheral ammonia and blood brain barrier structure and function after methamphetamine

NA Northrop, LE Halpin, BK Yamamoto - Neuropharmacology, 2016 - Elsevier
An effect of the widely abuse psychostimulant, methamphetamine (Meth), is blood-brain-
barrier (BBB) disruption; however, the mechanism by which Meth causes BBB disruption …

Subchronic exposure to di-(2-ethylhexyl) phthalate (DEHP) elicits blood–brain barrier dysfunction and neuroinflammation in male C57BL/6J mice

W Ren, N Liu, Y Shen, X Wang, Q Zhou, C Rui, X Yang… - Toxicology, 2023 - Elsevier
Abstract Background Exposure to di-(2-ethylhexyl) phthalate (DEHP) can cause
neurotoxicity but the mechanism is not clear. Blood brain barrier (BBB) is one of the most …

[HTML][HTML] Exercise protects against methamphetamine-induced aberrant neurogenesis

M Park, H Levine, M Toborek - Scientific reports, 2016 - nature.com
While no effective therapy is available for the treatment of methamphetamine (METH)-
induced neurotoxicity, aerobic exercise is being proposed to improve depressive symptoms …

Current preclinical studies on neuroinflammation and changes in blood–brain barrier integrity by MDMA and methamphetamine

E O'Shea, A Urrutia, AR Green, MI Colado - Neuropharmacology, 2014 - Elsevier
The blood–brain barrier (BBB) is essential in the maintenance of brain homeostasis both by
preserving normal brain functioning and also by protecting the brain from exposure to a …