Infliximab counteracts tumor necrosis factor-α-enhanced induction of matrix metalloproteinases that degrade claudin and occludin in non-pigmented ciliary epithelium
H Yamada, M Yoneda, S Inaguma, D Watanabe… - Biochemical …, 2013 - Elsevier
Infliximab, a monoclonal antibody directed against human tumor necrosis factor-alpha (TNF-
α), effectively treats anterior uveitis, which can accompany Behçet's disease. Here, we …
α), effectively treats anterior uveitis, which can accompany Behçet's disease. Here, we …
Methamphetamine is not toxic but disrupts the cell cycle of blood–brain barrier endothelial cells
D Fisher, K Gamieldien, PS Mafunda - Neurotoxicity Research, 2015 - Springer
The cytotoxic effects of methamphetamine (MA) are well established to be caused via
induced oxidative stress which in turn compromises the core function of the blood–brain …
induced oxidative stress which in turn compromises the core function of the blood–brain …
Methamphetamine enhances caveolar transport of therapeutic agents across the rodent blood-brain barrier
JH Chang, C Greene, K Frudd, LA Dos Santos… - Cell Reports …, 2022 - cell.com
The blood-brain barrier (BBB) restricts clinically relevant accumulation of many therapeutics
in the CNS. Low-dose methamphetamine (METH) induces fluid-phase transcytosis across …
in the CNS. Low-dose methamphetamine (METH) induces fluid-phase transcytosis across …
The protective effect of gastrodin against the synergistic effect of HIV-Tat protein and METH on the blood–brain barrier via glucose transporter 1 and glucose …
J Li, J Huang, Y He, W Wang, CK Leung… - Toxicology …, 2021 - academic.oup.com
Many individuals infected with human immunodeficiency virus (HIV) are also afflicted with
HIV-associated neurocognitive disorders (HANDs). Methamphetamine (METH) abuse puts …
HIV-associated neurocognitive disorders (HANDs). Methamphetamine (METH) abuse puts …
Methamphetamine-induced encephalopathy in the absence of hyperammonemia
JM Rabbany, K Fitzgerald, J Bowman, F Dong… - BMC psychiatry, 2023 - Springer
Background Methamphetamine is an addictive drug with various effects on the
neurotransmitters in the central nervous system. Methamphetamine-induced …
neurotransmitters in the central nervous system. Methamphetamine-induced …
Three-dimensional explant platform for studies on choroid plexus epithelium
N Petersen, L Torz, KHR Jensen, GM Hjortø… - Frontiers in cellular …, 2020 - frontiersin.org
The choroid plexus (CP) plays a major role in controlling the entry of substances and
immune cells into the brain as it forms the blood-cerebrospinal fluid barrier (BCSFB) in the …
immune cells into the brain as it forms the blood-cerebrospinal fluid barrier (BCSFB) in the …
Increased AGE-RAGE axis stress in methamphetamine (MA) abuse and MA-induced psychosis: associations with oxidative stress and increased atherogenicity
Background and aims Methamphetamine (MA)-induced psychosis (MIP) is associated with
increased oxidative toxicity (especially lipid peroxidation) and lowered antioxidant defenses …
increased oxidative toxicity (especially lipid peroxidation) and lowered antioxidant defenses …
Neonatal excitotoxicity modifies blood‐brain barrier properties increasing its susceptibility to hypertonic shock in adulthood
BF Fajardo‐Fregoso… - International Journal …, 2020 - Wiley Online Library
Early responses to a neurological excitotoxic process include blood‐brain barrier (BBB)
impairment and overexpression of vascular endothelial growth factor (VEGF), but the long …
impairment and overexpression of vascular endothelial growth factor (VEGF), but the long …
Apolipoprotein-E controls adenosine triphosphate-binding cassette transporters ABCB1 and ABCC1 on cerebral microvessels after methamphetamine intoxication
Background and Purpose—Methamphetamine is a powerful addictive, which has been
associated with ischemic stroke and brain hemorrhage in humans. Whether and how …
associated with ischemic stroke and brain hemorrhage in humans. Whether and how …
Forensic application of aquaporins
Aquaporins (AQPs) are a family of water channel proteins that primarily elicit the basic
functions of water transport and osmotic homeostasis. To date, at least 17 mammalian AQPs …
functions of water transport and osmotic homeostasis. To date, at least 17 mammalian AQPs …