Diseases associated with chronic inflammation constitute a major health burden across the
world. As central instigators of the inflammatory response to infection and tissue damage …

Ovarian cancer (OC) is one of the most common malignancies that causes death in women
and is a heterogeneous disease with complex molecular and genetic changes. Because of …

Aims Multiple sclerosis (MS) still maintains increasing prevalence and poor prognosis, while
glucagon‐like peptide‐1 receptor (GLP‐1R) agonists show excellent neuroprotective …

Multiple sclerosis (MS) is an autoimmune demyelinating neurodegenerative disease of the
central nervous system (CNS) due to injury of the myelin sheath by immune cells. The …

The nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)
inflammasome is an important part of the natural immune system that plays an important role …

Neuroinflammation is initiated with an aberrant innate immune response in the central
nervous system (CNS) and is involved in many neurological diseases. Inflammasomes are …

The liver is in charge of a wide range of critical physiological processes and it plays an
important role in activating the innate immune system which elicits the inflammatory events …

Aberrant NLRP3 activation has been implicated in the pathogenesis of numerous
inflammation-associated diseases. However, no small molecular inhibitor that directly …

Background Innate and adaptive immunity are two different parts of the immune system that
have different characteristics and work together to provide immune protection …

Sepsis is defined as “a life‐threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection.” At present, sepsis continues to …