Pathology and astrocytes in autism
G Vakilzadeh, V Martinez-Cerdeño - Neuropsychiatric Disease and …, 2023 - Taylor & Francis
A distinct pathology for autism spectrum disorder (ASD) remains elusive. Human and animal
studies have focused on investigating the role of neurons in ASD. However, recent studies …
studies have focused on investigating the role of neurons in ASD. However, recent studies …
Inflammation and the potential implication of macrophage-microglia polarization in human ASD: an overview
Autism spectrum disorder (ASD) is a heterogeneous collection of neurodevelopmental
disorders, difficult to diagnose and currently lacking treatment options. The possibility of …
disorders, difficult to diagnose and currently lacking treatment options. The possibility of …
Guggulsterone mediated JAK/STAT and PPAR-gamma modulation prevents neurobehavioral and neurochemical abnormalities in propionic acid-induced …
Autism spectrum disorder is a neurodevelopmental disorder marked by repetitive behaviour,
challenges in verbal and non-verbal communication, poor socio-emotional health, and …
challenges in verbal and non-verbal communication, poor socio-emotional health, and …
[HTML][HTML] Immp2l knockdown in male mice increases stimulus-driven instrumental behaviour but does not alter goal-directed learning or neuron density in cortico …
Cortico-striatal neurocircuits mediate goal-directed and habitual actions which are
necessary for adaptive behaviour. It has recently been proposed that some of the core …
necessary for adaptive behaviour. It has recently been proposed that some of the core …
Distinct patterns of GABAergic interneuron pathology in autism are associated with intellectual impairment and stereotypic behaviors
Autism spectrum disorder is a neurodevelopmental condition characterized by deficits in
social communication and repetitive behaviors. How specific anatomical alterations …
social communication and repetitive behaviors. How specific anatomical alterations …
Decreased number and increased activation state of astrocytes in gray and white matter of the prefrontal cortex in autism
The cerebral cortex presents with alterations in the number of specific cell types in autism
spectrum disorder (ASD). Astrocytes have many functions in the brain including a role in …
spectrum disorder (ASD). Astrocytes have many functions in the brain including a role in …
Srsf1 and Elavl1 act antagonistically on neuronal fate choice in the developing neocortex by controlling TrkC receptor isoform expression
AI Weber, S Parthasarathy, E Borisova… - Nucleic Acids …, 2023 - academic.oup.com
The seat of higher-order cognitive abilities in mammals, the neocortex, is a complex
structure, organized in several layers. The different subtypes of principal neurons are …
structure, organized in several layers. The different subtypes of principal neurons are …
Lights on for autism: exploring Photobiomodulation as an effective therapeutic option
C Hamilton, A Liebert, V Pang, P Magistretti… - Neurology …, 2022 - mdpi.com
Autism is a neurodevelopmental condition that starts in childhood and continues into
adulthood. The core characteristics include difficulties with social interaction and …
adulthood. The core characteristics include difficulties with social interaction and …
4-hydroxyisoleucine mediated IGF-1/GLP-1 signalling activation prevents propionic acid-induced autism-like behavioural phenotypes and neurochemical defects in …
Autism is a neuropsychiatric disorder characterized by a neurotransmitter imbalance that
impairs neurodevelopment processes. Autism development is marked by communication …
impairs neurodevelopment processes. Autism development is marked by communication …
Comparative analyses of the Smith− Magenis syndrome protein RAI1 in mice and common marmoset monkeys
YT Chang, YJ Lee, M Haque, HC Chang… - Journal of …, 2024 - Wiley Online Library
Abstract Retinoic acid‐induced 1 (RAI1) encodes a transcriptional regulator critical for brain
development and function. RAI1 haploinsufficiency in humans causes a syndromic autism …
development and function. RAI1 haploinsufficiency in humans causes a syndromic autism …