Regulated cell death (RCD) is a ubiquitous process in living organisms that is essential for
tissue homeostasis or to restore biological balance under stress. Over the decades, various …

Parkinson's disease (PD) is the second most common neurodegenerative disease. PD
patients exhibit motor symptoms such as akinesia/bradykinesia, tremor, rigidity, and postural …

Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of motor neurons in
the motor cortex, brainstem, and spinal cord. Although ALS is considered a motor neuron …

Resveratrol is a natural polyphenolic compound with a wide range of biological activities
such as antioxidant, anti-carcinogenic, anti-obesity, anti-aging, anti-inflammatory …

Inflammation is one of the pathogenic processes in Parkinson's disease (PD). Dopamine
receptor agonist pramipexole (PPX) is extensively used for PD treatment in clinics. A number …

Evidence suggests that various innate immune system components are involved in
pathological inflammatory conditions. Among these components, the NLR family pyrin …

Parkinson's disease (PD) is a common neurodegenerative disorder caused by the loss of
dopamine neurons in the substantia nigra and the formation of Lewy bodies, which are …

Depression is a common and serious mental disorder. Data on its pathogenesis remain
unclear and the options of drug treatments are limited. Here, we explored the role of …

Nerve injury and nerve pain are common diseases caused by neuroinflammation.
Numerous studies have shown that the activation of NLRP3 (nod-like receptor family, pyrin …

Parkinson's disease (PD) is a common neurodegenerative condition for which no approved
treatment exists to prevent collective neuronal death. There is ample evidence that …