Role of mitochondrial quality surveillance in myocardial infarction: from bench to bedside
Myocardial infarction (MI) is the irreversible death of cardiomyocyte secondary to prolonged
lack of oxygen or fresh blood supply. Historically considered as merely cardiomyocyte …
lack of oxygen or fresh blood supply. Historically considered as merely cardiomyocyte …
The molecular basis of predicting atherosclerotic cardiovascular disease risk
M Nayor, KJ Brown, RS Vasan - Circulation research, 2021 - Am Heart Assoc
Atherosclerotic cardiovascular disease (ASCVD) proceeds through a series of stages:
initiation, progression (or regression), and complications. By integrating known biology …
initiation, progression (or regression), and complications. By integrating known biology …
MRP1-dependent extracellular release of glutathione induces cardiomyocyte ferroptosis after ischemia-reperfusion
G Ichihara, Y Katsumata, Y Sugiura… - Circulation …, 2023 - Am Heart Assoc
BACKGROUND: The membrane components of cardiomyocytes are rich in polyunsaturated
fatty acids, which are easily oxidized. Thus, an efficient glutathione-based lipid redox system …
fatty acids, which are easily oxidized. Thus, an efficient glutathione-based lipid redox system …
Predictive metabolites for incident myocardial infarction: a two-step meta-analysis of individual patient data from six cohorts comprising 7897 individuals from the …
Aims Myocardial infarction (MI) is a major cause of death and disability worldwide. Most
metabolomics studies investigating metabolites predicting MI are limited by the participant …
metabolomics studies investigating metabolites predicting MI are limited by the participant …
The role of mitochondrial quality control in anthracycline‐induced cardiotoxicity: from bench to bedside
Y Li, R Lin, X Peng, X Wang, X Liu, L Li… - Oxidative Medicine …, 2022 - Wiley Online Library
Cardiotoxicity is the major side effect of anthracyclines (doxorubicin, daunorubicin,
epirubicin, and idarubicin), though being the most commonly used chemotherapy drugs and …
epirubicin, and idarubicin), though being the most commonly used chemotherapy drugs and …
Exosomes of human umbilical cord MSCs protect against hypoxia/reoxygenation-induced pyroptosis of cardiomyocytes via the miRNA-100-5p/FOXO3/NLRP3 …
C Liang, Y Liu, H Xu, J Huang, Y Shen… - … in Bioengineering and …, 2021 - frontiersin.org
Background Acute myocardial infarction (AMI) is one of the leading causes of morbidity and
death worldwide. Studies have indicated that microRNAs in mesenchymal stem cell (MSC) …
death worldwide. Studies have indicated that microRNAs in mesenchymal stem cell (MSC) …
Prospects for precision medicine in acute myocardial infarction: patient-level insights into myocardial injury and repair
M Alkhalil, GL De Maria, N Akbar, N Ruparelia… - Journal of Clinical …, 2023 - mdpi.com
Highlights What Is Already Known and How This Shapes the Future Highly controlled
experimental studies have illustrated the importance of ischaemia time in relation to myocyte …
experimental studies have illustrated the importance of ischaemia time in relation to myocyte …
Defining acute coronary syndrome through metabolomics
A Surendran, N Atefi, H Zhang, M Aliani, A Ravandi - Metabolites, 2021 - mdpi.com
As an emerging platform technology, metabolomics offers new insights into the
pathomechanisms associated with complex disease conditions, including cardiovascular …
pathomechanisms associated with complex disease conditions, including cardiovascular …
Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response
Mechanisms linking immune sensing of DNA danger signals in the extracellular
environment to innate pathways in the cytosol are poorly understood. Here, we identify a …
environment to innate pathways in the cytosol are poorly understood. Here, we identify a …
Electroacupuncture interventions alleviates myocardial ischemia reperfusion injury through regulating gut microbiota in rats
H Bai, RJ Gu, LY Chen, Y Qian, ML Yu, SL Xu… - Microvascular …, 2021 - Elsevier
Electroacupuncture (EA) intervention has a remarkable cardioprotection against myocardial
ischemia reperfusion injury (MIRI). Recently, it has been suggested that the gut microbiota …
ischemia reperfusion injury (MIRI). Recently, it has been suggested that the gut microbiota …