Dementia is a progressive neurodegenerative disorder with cognitive dysfunction, and is
often complicated by behavioral and psychological symptoms of dementia (BPSD) including …

Japanese traditional herbal medicine (Kampo) has its origins in traditional Chinese
medicine (TCM). It was introduced to Japan in the middle of the sixth century and has …

Background Koumine is the most abundant alkaloid extracted from Gelsemium elegans
Benth.. Preliminary studies by our research group have shown that koumine has significant …

The aim of this study was to examine changes in rat emotional behavior and determine
differences in the expression of GABA-A receptor alpha-2 subunits in brain structures of low …

Stress contributes, as a risk factor, to such psychological disorders as anxiety. The effects of
electrical lesions in the basolateral amygdala nucleus (BLA) were investigated on the …

Cnidium officinale Makino (COM), a perennial herbaceous plant in the Apiaceous family,
widely distribute in Eastern Asia and Asia‐Temperate. It has a long history application as a …

α-Casozepine (α-CZP) is an anxiolytic-like bioactive decapeptide derived from bovine αs1-
casein. The N-terminal peptide YLGYL was previously identified after proteolysis of the …

Objective (s): Stress alters sensory and cognitive function in humans and animals.
Angiotensin (AT) receptors have demonstrated well-established interactions in sets of …

Brain stroke continues to claim the lives of million people every year. To build the effective
strategies for stroke treatment it is necessary to understand the neuroprotective mechanisms …

Ethnopharmacological relevance Yokukansan, a traditional Japanese (Kampo) medicine,
has recently been used to treat the behavioral and psychological symptoms of dementia …