Neutrophils: important contributors to tumor progression and metastasis
A Swierczak, KA Mouchemore, JA Hamilton… - Cancer and Metastasis …, 2015 - Springer
The presence of neutrophils in tumors has traditionally been considered to be indicative of a
failed immune response against cancers. However, there is now evidence showing that …
failed immune response against cancers. However, there is now evidence showing that …
Immune microenvironment in tumor progression: characteristics and challenges for therapy
The tumor microenvironment plays a critical role in cancer development, progression, and
control. The molecular and cellular nature of the tumor immune microenvironment influences …
control. The molecular and cellular nature of the tumor immune microenvironment influences …
Remodeled tumor immune microenvironment (TIME) parade via natural killer cells reprogramming in breast cancer
MM Elanany, DM Mostafa, NM Hamdy - Life Sciences, 2023 - Elsevier
Breast cancer (BC) is the main cause of cancer-related mortality among women globally.
Despite substantial advances in the identification and management of primary tumors …
Despite substantial advances in the identification and management of primary tumors …
[HTML][HTML] Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived …
MM Shenouda, A Gillgrass, T Nham, R Hogg… - Breast Cancer …, 2017 - Springer
Background Natural killer (NK) cells play a critical role in cancer immunosurveillance.
Recent developments in NK cell ex-vivo expansion makes it possible to generate millions of …
Recent developments in NK cell ex-vivo expansion makes it possible to generate millions of …
The breast tumor microenvironment alters the phenotype and function of natural killer cells
T Krneta, A Gillgrass, M Chew, AA Ashkar - Cellular & molecular …, 2016 - nature.com
Natural killer (NK) cells are innate immune cells with the ability to identify and eliminate
transformed cells. However, within tumors, many studies have described NK cells as non …
transformed cells. However, within tumors, many studies have described NK cells as non …
Pregnancy and breast cancer
R Subramani, R Lakshmanaswamy - Progress in molecular biology and …, 2017 - Elsevier
Breast cancer is the most commonly diagnosed type of cancer among women worldwide.
The majority of breast cancers are sporadic and the etiology is not well understood. Several …
The majority of breast cancers are sporadic and the etiology is not well understood. Several …
NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery
R Spada, JM Rojas, S Pe´ rez-Yagu¨ e… - Journal of Leucocyte …, 2015 - academic.oup.com
NK cells are a major component of the immune system, and alterations in their activity are
correlated with various autoimmune diseases. In the present work, we observed an …
correlated with various autoimmune diseases. In the present work, we observed an …
Micro RNA function in NK‐cell biology
AM Beaulieu, NA Bezman, JE Lee… - Immunological …, 2013 - Wiley Online Library
The important role of micro RNA s in directing immune responses has become increasingly
clear. Here, we highlight discoveries uncovering the role of specific micro RNA s in …
clear. Here, we highlight discoveries uncovering the role of specific micro RNA s in …
Balance between activating NKG 2D, DNAM‐1, NK p44 and NK p46 and inhibitory CD 94/NKG 2A receptors determine natural killer degranulation towards …
N Nielsen, V Pascal, AER Fasth, Y Sundström… - …, 2014 - Wiley Online Library
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation
and synovial hyperplasia leading to progressive joint destruction. Fibroblast‐like …
and synovial hyperplasia leading to progressive joint destruction. Fibroblast‐like …
Long-chain polyunsaturated omega-3 fatty acids reduce multiple myeloma exosome-mediated suppression of NK cell cytotoxicity
Background Despite the advances in the treatment of multiple myeloma (MM), complete
remission is usually challenging. The interactions between tumor and host cells, in which …
remission is usually challenging. The interactions between tumor and host cells, in which …