Roles of tumor-associated macrophages in anti-PD-1/PD-L1 immunotherapy for solid cancers

H Zhang, L Liu, J Liu, P Dang, S Hu, W Yuan, Z Sun… - Molecular Cancer, 2023 - Springer
In recent years, tumor immunotherapy has made significant progress. However, tumor
immunotherapy, particularly immune checkpoint inhibitors (eg, PD-1/PD-L1 inhibitors) …

Immunotherapy: reshape the tumor immune microenvironment

B Lv, Y Wang, D Ma, W Cheng, J Liu, T Yong… - Frontiers in …, 2022 - frontiersin.org
Tumor immune microenvironment (TIME) include tumor cells, immune cells, cytokines, etc.
The interactions between these components, which are divided into anti-tumor and pro …

Role of tumor microenvironment in cancer progression and therapeutic strategy

Q Wang, X Shao, Y Zhang, M Zhu, FXC Wang… - Cancer …, 2023 - Wiley Online Library
Cancer is now considered a tumor microenvironment (TME) disease, although it was
originally thought to be a cell and gene expression disorder. Over the past 20 years …

mRNA vaccines for cancer immunotherapy

YL Vishweshwaraiah, NV Dokholyan - Frontiers in immunology, 2022 - frontiersin.org
Immunotherapy has emerged as a breakthrough strategy in cancer treatment. mRNA
vaccines are an attractive and powerful immunotherapeutic platform against cancer because …

ER-targeting PDT converts tumors into in situ therapeutic tumor vaccines

X Liu, Y Liu, X Li, J Huang, X Guo, J Zhang, Z Luo… - Acs Nano, 2022 - ACS Publications
A therapeutic tumor vaccine is a promising approach to cancer treatment. One of its
strategies is to treat patient-derived tumor cells in vitro and then administer them in vivo to …

Acid‐ionizable iron nanoadjuvant augments STING activation for personalized vaccination immunotherapy of cancer

F Chen, T Li, H Zhang, M Saeed, X Liu… - Advanced …, 2023 - Wiley Online Library
The critical challenge for cancer vaccine‐induced T‐cell immunity is the sustained activation
of antigen cross‐presentation in antigen‐presenting cells (APCs) with innate immune …

Cancer vaccine therapeutics: limitations and effectiveness—A literature review

M Kaczmarek, J Poznańska, F Fechner, N Michalska… - Cells, 2023 - mdpi.com
In recent years, there has been a surge of interest in tumor microenvironment-associated
cancer vaccine therapies. These innovative treatments aim to activate and enhance the …

[HTML][HTML] Hydrogel-enabled, local administration and combinatorial delivery of immunotherapies for cancer treatment

A Erfani, AE Diaz, PS Doyle - Materials Today, 2023 - Elsevier
Throughout the last decade, interventions to engineer the immune system called
immunotherapy have revolutionized the fields of oncology and autoimmune disease …

Recent advances in microneedles-based drug delivery device in the diagnosis and treatment of cancer

V Singh, P Kesharwani - Journal of Controlled Release, 2021 - Elsevier
Microneedles are unique, novel and an effective approach designed to deliver therapeutic
agents and immunobiologicals in several diseases. These tiny needle patches are designed …

Integrating single-cell analysis and machine learning to create glycosylation-based gene signature for prognostic prediction of uveal melanoma

J Liu, P Zhang, F Yang, K Jiang, S Sun, Z Xia… - Frontiers in …, 2023 - frontiersin.org
Background Increasing evidence suggests a correlation between glycosylation and the
onset of cancer. However, the clinical relevance of glycosylation-related genes (GRGs) in …