Evolution and otitis media: a review, and a model to explain high prevalence in indigenous populations

MF Bhutta - Human biology, 2015 - BioOne
Otitis media (OM; inflammation of the middle ear) comprises a group of disorders that are
among the most common disorders of childhood. OM is also heritable and has effects on …

Mechanical damage of tympanic membrane in relation to impulse pressure waveform–a study in chinchillas

RZ Gan, D Nakmali, XD Ji, K Leckness, Z Yokell - Hearing research, 2016 - Elsevier
Mechanical damage to middle ear components in blast exposure directly causes hearing
loss, and the rupture of the tympanic membrane (TM) is the most frequent injury of the ear …

Laser interferometry measurements of middle ear fluid and pressure effects on sound transmission

RZ Gan, C Dai, MW Wood - The Journal of the Acoustical Society of …, 2006 - pubs.aip.org
An otitis media with effusion model in human temporal bones with two laser vibrometers was
created in this study. By measuring the displacement of the stapes from the medial side of …

Middle ear pressure during sleep and the effects of continuous positive airway pressure

JJ Thom, ML Carlson, CLW Driscoll, EK St Louis… - American Journal of …, 2015 - Elsevier
Abstract Purpose Prior studies evaluating Eustachian tube physiology, baseline middle ear
pressure (MEP), and the effects of continuous positive airway pressure (CPAP) have been …

Middle ear of human and pig: a comparison of structures and mechanics

M Hoffstetter, F Lugauer, S Kundu, S Wacker… - 2011 - degruyter.com
Introduction: Animal studies are an essential method to evaluate implants for the middle ear
prior to clinical studies. New Zealand rabbits, guinea pigs and chinchillas are, among other …

Effect of middle ear fluid on sound transmission and auditory brainstem response in guinea pigs

X Guan, RZ Gan - Hearing research, 2011 - Elsevier
Combined measurements of middle ear transfer function and auditory brainstem response
(ABR) in live guinea pigs with middle ear effusion (MEE) are reported in this paper. The MEE …

Conductive hearing loss induced by experimental middle-ear effusion in a chinchilla model reveals impaired tympanic membrane-coupled ossicular chain movement

JL Thornton, KM Chevallier, K Koka… - Journal of the …, 2013 - Springer
Otitis media with effusion (OME) occurs when fluid collects in the middle-ear space behind
the tympanic membrane (TM). As a result of this effusion, sounds can become attenuated by …

Mechanisms of tympanic membrane and incus mobility loss in acute otitis media model of guinea pig

X Guan, RZ Gan - Journal of the Association for Research in …, 2013 - Springer
Acute otitis media (AOM) is a rapid infection of middle ear due to bacterial or viral invasion.
The infection commonly leads to negative pressure and purulent effusion in the middle ear …

Mechanism and rate of middle ear fluid absorption

P Petrova, S Freeman, H Sohmer - Audiology and Neurotology, 2007 - karger.com
Several mechanisms have been suggested to explain the clearance of fluids from the middle
ear. These include a pumping action through the eustachian tube, mucociliary beating …

Middle ear biomechanics in chinchilla model of acute otitis media

X Guan - 2014 - shareok.org
Acute otitis media (AOM) is a rapid onset of infection in the middle ear and the most
frequently diagnosed disease in pediatric population. Conductive hearing loss is the most …