Current status of the diagnosis and management of osteoporosis
A Aibar-Almazán, A Voltes-Martínez… - International journal of …, 2022 - mdpi.com
Osteoporosis has been defined as the silent disease of the 21st century, becoming a public
health risk due to its severity, chronicity and progression and affecting mainly …
health risk due to its severity, chronicity and progression and affecting mainly …
Molecular mechanisms and emerging therapeutics for osteoporosis
JY Noh, Y Yang, H Jung - International journal of molecular sciences, 2020 - mdpi.com
Osteoporosis is the most common chronic metabolic bone disease. It has been estimated
that more than 10 million people in the United States and 200 million men and women …
that more than 10 million people in the United States and 200 million men and women …
The shift in the balance between osteoblastogenesis and adipogenesis of mesenchymal stem cells mediated by glucocorticoid receptor
L Han, B Wang, R Wang, S Gong, G Chen… - Stem cell research & …, 2019 - Springer
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into several
tissues, such as bone, cartilage, and fat. Glucocorticoids affect a variety of biological …
tissues, such as bone, cartilage, and fat. Glucocorticoids affect a variety of biological …
The potential use of mesenchymal stem cells and their derived exosomes for orthopedic diseases treatment
Musculoskeletal disorders (MSDs) are conditions that can affect muscles, bones, and joints.
These disorders are very painful and severely limit patients' mobility and are more common …
These disorders are very painful and severely limit patients' mobility and are more common …
[HTML][HTML] Regional specialization and fate specification of bone stromal cells in skeletal development
KK Sivaraj, HW Jeong, B Dharmalingam, D Zeuschner… - Cell Reports, 2021 - cell.com
Bone stroma contributes to the regulation of osteogenesis and hematopoiesis but also to
fracture healing and disease processes. Mesenchymal stromal cells from bone (BMSCs) …
fracture healing and disease processes. Mesenchymal stromal cells from bone (BMSCs) …
m6A methylation of precursor-miR-320/RUNX2 controls osteogenic potential of bone marrow-derived mesenchymal stem cells
G Yan, YE Yuan, M He, R Gong, H Lei, H Zhou… - … Therapy-Nucleic Acids, 2020 - cell.com
Methyltransferase-like 3 (METTL3) is the main enzyme for N 6-methyladenosine (m 6 A)-
based methylation of RNAs and it has been implicated in many biological and …
based methylation of RNAs and it has been implicated in many biological and …
Cell-based therapy in thin endometrium and Asherman syndrome
N Gharibeh, L Aghebati-Maleki, J Madani… - Stem Cell Research & …, 2022 - Springer
Numerous treatment strategies have so far been proposed for treating refractory thin
endometrium either without or with the Asherman syndrome. Inconsistency in the …
endometrium either without or with the Asherman syndrome. Inconsistency in the …
Molecular-based treatment strategies for osteoporosis: a literature review
Y Ukon, T Makino, J Kodama, H Tsukazaki… - International journal of …, 2019 - mdpi.com
Osteoporosis is an unavoidable public health problem in an aging or aged society. Anti-
resorptive agents (calcitonin, estrogen, and selective estrogen-receptor modulators …
resorptive agents (calcitonin, estrogen, and selective estrogen-receptor modulators …
[HTML][HTML] Enhanced osseointegration of three-dimensional supramolecular bioactive interface through osteoporotic microenvironment regulation
H Bai, Y Zhao, C Wang, Z Wang, J Wang, H Liu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Purpose: Osteoporosis is more likely to cause serious complications after joint replacement,
mainly due to physiological defects of endogenous osteogenic cells and the pathological …
mainly due to physiological defects of endogenous osteogenic cells and the pathological …
New frontiers in osteoporosis therapy
C Cheng, K Wentworth… - Annual Review of …, 2020 - annualreviews.org
Current osteoporosis medications reduce fractures significantly but have rare and serious
adverse effects (osteonecrosis of the jaw, atypical femoral fractures) that may limit their …
adverse effects (osteonecrosis of the jaw, atypical femoral fractures) that may limit their …