Recent reports have described the interactions of muscle and bone. Various muscle-derived
humoral factors, known as myokines, affect bone. Although extracellular vesicles (EVs) play …

Orthobiologics are organic and synthetic materials that help in the cure of musculo-skeletal
problems and are utilized in Orthopaedic Surgery, both in and out of the surgical theater, to …

Extracellular vesicles (EVs) are nanoparticles that include exosomes, microvesicles, and
apoptotic bodies; they interact with target cell surface receptors and transport contents …

Bone and joint diseases are prevalent and often fatal conditions in elderly individuals.
Additionally, bone-derived cells may release exosomes that package and distribute a range …

Purpose To analyze preclinical bone regeneration studies employing mesenchymal stromal
cell (MSC)-derived extracellular vesicles (EVs) and highlight any commonalities in EV …

The healing of bone fractures can become aberrant and lead to nonunions which in turn
have a negative impact on patient health. Understanding why a bone fails to normally heal …

The present study aimed to explore the expression of microribonucleic acid
(microRNA)(miR)‑205 in bone tissues and serum of elderly female patients with type 2 …

Background Nonunions remain a challenging post-traumatic complication that often leads to
a financial and health burden that affects the patient's quality of life. Despite a wealth of …

During the past several years, pre-clinical experiments have established that microRNAs
(miRNAs), small non-coding RNAs, serve as key regulatory molecules of fracture healing …

Osteoporosis is a degenerative disease affecting millions of elderly people globally and
increases the risk of bone fractures due to the reduced bone density. Drugs are normally …