[HTML][HTML] Heavy metals and pesticides toxicity in agricultural soil and plants: Ecological risks and human health implications

A Alengebawy, ST Abdelkhalek, SR Qureshi, MQ Wang - Toxics, 2021 - mdpi.com
Environmental problems have always received immense attention from scientists. Toxicants
pollution is a critical environmental concern that has posed serious threats to human health …

Hazardous effects of chemical pesticides on human health–Cancer and other associated disorders

A Sabarwal, K Kumar, RP Singh - Environmental toxicology and …, 2018 - Elsevier
Poisoning from pesticides is a global public health problem and accounts for nearly 300,000
deaths worldwide every year. Exposure to pesticides is inevitable; there are different modes …

Oxidative stress and cancer

JE Klaunig - Current pharmaceutical design, 2018 - ingentaconnect.com
Background: Cancer is considered a major cause of death worldwide. The etiology of cancer
is linked to environmental and genetic inheritance causes. Approximately 90 percent of all …

[HTML][HTML] Risk factors for gastric cancer: a systematic review

AR Yusefi, KB Lankarani, P Bastani… - Asian Pacific journal …, 2018 - ncbi.nlm.nih.gov
Objective: Gastric cancer is one of the leading causes of death worldwide, with many
influences contributing to the disease. The aim of this study was to identify the most …

The immune system in cancer pathogenesis: potential therapeutic approaches

PH Pandya, ME Murray, KE Pollok… - Journal of …, 2016 - Wiley Online Library
Interplay among immune activation and cancer pathogenesis provides the framework for a
novel subspecialty known as immunooncology. In the rapidly evolving field of …

Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways

AJ Schetter, NHH Heegaard, CC Harris - Carcinogenesis, 2010 - academic.oup.com
Chronic inflammation and infection are major causes of cancer. There are continued
improvements to our understanding of the molecular connections between inflammation and …

Oxidative stress and oxidative damage in chemical carcinogenesis

JE Klaunig, Z Wang, X Pu, S Zhou - Toxicology and applied pharmacology, 2011 - Elsevier
Reactive oxygen species (ROS) are induced through a variety of endogenous and
exogenous sources. Overwhelming of antioxidant and DNA repair mechanisms in the cell by …

Cytokines and their relationship to the symptoms and outcome of cancer

B Seruga, H Zhang, LJ Bernstein, IF Tannock - Nature Reviews Cancer, 2008 - nature.com
Tumours contain immune cells and a network of pro-and anti-inflammatory cytokines, which
collaborate in the development and progression of cancer. Cytokine profiles might prove to …

Germline genomic variants associated with childhood acute lymphoblastic leukemia

LR Treviño, W Yang, D French, SP Hunger… - Nature …, 2009 - nature.com
Abstract Using the Affymetrix 500K Mapping array and publicly available genotypes, we
identified 18 SNPs whose allele frequency differed significantly (P< 1× 10− 5) between …

Metabolism and biomarkers of heterocyclic aromatic amines in molecular epidemiology studies: lessons learned from aromatic amines

RJ Turesky, L Le Marchand - Chemical research in toxicology, 2011 - ACS Publications
Aromatic amines and heterocyclic aromatic amines (HAAs) are structurally related classes of
carcinogens that are formed during the combustion of tobacco or during the high …