Autonomic control of cerebral blood flow: fundamental comparisons between peripheral and cerebrovascular circulations in humans

JL Koep, CE Taylor, JS Coombes… - The Journal of …, 2022 - Wiley Online Library
Understanding the contribution of the autonomic nervous system to cerebral blood flow
(CBF) control is challenging, and interpretations are unclear. The identification of calcium …

Neuronal networks in hypertension: recent advances

PG Guyenet, RL Stornetta, GMPR Souza… - …, 2020 - Am Heart Assoc
Neurogenic hypertension is associated with excessive sympathetic nerve activity to the
kidneys and portions of the cardiovascular system. Here we examine the brain regions that …

Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow

N Marina, IN Christie, A Korsak, M Doronin… - Nature …, 2020 - nature.com
Astrocytes provide neurons with essential metabolic and structural support, modulate
neuronal circuit activity and may also function as versatile surveyors of brain milieu, tuned to …

Mechanosensory signaling in astrocytes

EA Turovsky, A Braga, Y Yu, N Esteras… - Journal of …, 2020 - Soc Neuroscience
Mechanosensitivity is a well-known feature of astrocytes, however, its underlying
mechanisms and functional significance remain unclear. There is evidence that astrocytes …

Anatomical basis and physiological role of cerebrospinal fluid transport through the murine cribriform plate

JN Norwood, Q Zhang, D Card, A Craine, TM Ryan… - Elife, 2019 - elifesciences.org
Cerebrospinal fluid (CSF) flows through the brain, transporting chemical signals and
removing waste. CSF production in the brain is balanced by a constant outflow of CSF, the …

Multipotential and systemic effects of traumatic brain injury

N Sabet, Z Soltani, M Khaksari - Journal of neuroimmunology, 2021 - Elsevier
Traumatic brain injury (TBI) is one of the leading causes of disability and mortality of people
at all ages. Biochemical, cellular and physiological events that occur during primary injury …

Rostral ventrolateral medulla, retropontine region and autonomic regulations

PG Guyenet, RL Stornetta - Autonomic Neuroscience, 2022 - Elsevier
The rostral half of the ventrolateral medulla (RVLM) and adjacent ventrolateral retropontine
region (henceforth RVLMRP) have been divided into various sectors by neuroscientists …

Fetal defenses against intrapartum head compression—implications for intrapartum decelerations and hypoxic-ischemic injury

CA Lear, JA Westgate, L Bennet, A Ugwumadu… - American Journal of …, 2023 - Elsevier
Uterine contractions during labor and engagement of the fetus in the birth canal can
compress the fetal head. Its impact on the fetus is unclear and still controversial. In this …

Influence of high‐intensity interval training to exhaustion on the directional sensitivity of the cerebral pressure‐flow relationship in young endurance‐trained men

F Abbariki, MA Roy, L Labrecque… - Physiological …, 2022 - Wiley Online Library
We previously reported subtle dynamic cerebral autoregulation (dCA) alterations following 6
weeks of high‐intensity interval training (HIIT) to exhaustion using transfer function analysis …

The sheep as a comprehensive animal model to investigate interdependent physiological pressure propagation and multiparameter influence on cerebrospinal fluid …

NE Trimmel, A Podgoršak, MF Oertel… - Frontiers in …, 2022 - frontiersin.org
The present study aims to develop a suitable animal model for evaluating the physiological
interactions between cerebrospinal fluid (CSF) dynamics, hemodynamics, and abdominal …