Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Mechanism of Candida pathogenesis: revisiting the vital drivers

IE Mba, EI Nweze - European Journal of Clinical Microbiology & Infectious …, 2020 - Springer
Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …

Mucin O-glycans are natural inhibitors of Candida albicans pathogenicity

J Takagi, K Aoki, BS Turner, S Lamont… - Nature chemical …, 2022 - nature.com
Mucins are large gel-forming polymers inside the mucus barrier that inhibit the yeast-to-
hyphal transition of Candida albicans, a key virulence trait of this important human fungal …

[HTML][HTML] Antimicrobial Compounds Produced by Vaginal Lactobacillus crispatus Are Able to Strongly Inhibit Candida albicans Growth, Hyphal Formation and …

S Wang, Q Wang, E Yang, L Yan, T Li… - Frontiers in …, 2017 - frontiersin.org
The female vaginal environment contains diverse microorganisms, and their interactions
play significant roles in health and disease. Lactobacillus species are the predominant …

[HTML][HTML] Antifungal activity, kinetics and molecular mechanism of action of garlic oil against Candida albicans

WR Li, QS Shi, HQ Dai, Q Liang, XB Xie, XM Huang… - Scientific reports, 2016 - nature.com
The antifungal activity, kinetics and molecular mechanism of action of garlic oil against
Candida albicans were investigated in this study using multiple methods. Using the …

[HTML][HTML] Targeting Virulence Factors of Candida albicans with Natural Products

QR Bu, MY Bao, Y Yang, TM Wang, CZ Wang - Foods, 2022 - mdpi.com
Natural products derived from natural resources, including nutritional functional food, play
an important role in human health. In recent years, the study of anti-fungal and other …

Intravital imaging-based genetic screen reveals the transcriptional network governing Candida albicans filamentation during mammalian infection

RS Wakade, LC Ristow, M Wellington, DJ Krysan - Elife, 2023 - elifesciences.org
Candida albicans is one of the most common human fungal pathogens. C. albicans
pathogenesis is tightly linked to its ability to under a morphogenetic transition from typically …

[HTML][HTML] Candida albicans Hyphae: From Growth Initiation to Invasion

JV Desai - Journal of Fungi, 2018 - mdpi.com
Candida albicans is a commensal resident of the human gastrointestinal and genital tracts.
Under conditions such as dysbiosis, host immune perturbances, or the presence of …

Mycobiome dysbiosis in women with intrauterine adhesions

NN Liu, X Zhao, JC Tan, S Liu, BW Li, WX Xu… - Microbiology …, 2022 - Am Soc Microbiol
The vaginal microbiota dysbiosis is closely associated with the development of reproductive
diseases. However, the contribution of mycobiome to intrauterine adhesion (IUA) disease …

Transcriptional control of hyphal morphogenesis in Candida albicans

S Villa, M Hamideh, A Weinstock, MN Qasim… - FEMS yeast …, 2020 - academic.oup.com
Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen
in humans. A morphological switch between unicellular budding yeast and multicellular …