In this article, we provide an analysis of noise propagation in a stochastic minimal model of
chemical self‐replication, where a given species can duplicate itself normally. A feedback …

Single-cell RNA sequencing, which quantifies cell transcriptomes, has seen widespread
adoption, accompanied by proliferation of analysis methods. However, there has been …

The chemical master equation and the stochastic simulation algorithm are widely used to
model the reaction kinetics inside living cells. It is thereby assumed that cell growth and …

Does embryonic development exhibit characteristic temporal features? This is apparent in
evolution, where evolutionary change has been shown to occur in bursts of activity. Using …

Gene activation is usually a non-Markovian process that has been modeled as various
frameworks that consist of multiple rate-limiting steps. Understanding the exact activation …

Noise-modulating chemicals can synergize with transcriptional activators in reactivating
latent HIV to eliminate latent HIV reservoirs. To understand the underlying biomolecular …

Most of the deaths from cancer are due to metastasis from primary tumor sites to other sites
in the body. Heterogeneity in tumors is associated with increased metastasis and a …

Computational models of biomolecular systems have been employed to advance
knowledge in many research areas. They have particular impact in modern areas such as …