The vaginal microbiota plays a significant role in health and disease of the female
reproductive tract. Next-generation sequencing techniques based upon the analysis of …

The human body is colonized by a vast number of microorganisms collectively referred to as
the human microbiota. One of the main microbiota body sites is the female genital tract …

Emerging evidence suggests associations between the vaginal microbiota (VMB)
composition, human papillomavirus (HPV) infection, and cervical intraepithelial neoplasia …

The innate defense system of the female mucosal genital tract involves a close and complex
interaction among the healthy vaginal microbiota, different cells, and various proteins that …

Vaginal microbiota dysbiosis, characterized by the loss of Lactobacillus dominance and
increase of microbial diversity, is closely related to gynecological diseases; thus …

The mechanism (s) by which Lactobacillus-dominated cervicovaginal microbiota provide a
barrier to Chlamydia trachomatis infection remain (s) unknown. Here we evaluate the impact …

Lactobacillus species dominate the microbiome in the lower genital tract of most
reproductive-age women. Producing lactic acid and H2O2, lactobacilli are believed to play …

The female reproductive tract harbours hundreds of bacterial species and produces
numerous metabolites. The uterine cervix is located between the upper and lower parts of …

Background Lactic acid (protonated lactate) has broad antimicrobial activity. Vaginal
lactobacilli produce lactic acid, and are known to confer protection against reproductive tract …

Lactobacillus species dominate the vaginal microbiota of healthy reproductive-age women
and protect the genitourinary tract from the attack of several infectious agents. Chlamydia …