Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions

SC Dyall, L Balas, NG Bazan, JT Brenna… - Progress in lipid …, 2022 - Elsevier
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …

Metabolism of tissue macrophages in homeostasis and pathology

SK Wculek, G Dunphy, I Heras-Murillo… - Cellular & molecular …, 2022 - nature.com
Cellular metabolism orchestrates the intricate use of tissue fuels for catabolism and
anabolism to generate cellular energy and structural components. The emerging field of …

Specialized pro-resolving mediator network: an update on production and actions

N Chiang, CN Serhan - Essays in Biochemistry, 2020 - portlandpress.com
Today, persistent and uncontrolled inflammation is appreciated to play a pivotal role in many
diseases, such as cardiovascular diseases, neurodegenerative diseases, metabolic …

Resolution of inflammation: An organizing principle in biology and medicine

D Panigrahy, MM Gilligan, CN Serhan… - Pharmacology & …, 2021 - Elsevier
The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …

Inflammation and skeletal muscle regeneration: leave it to the macrophages!

B Chazaud - Trends in immunology, 2020 - cell.com
Inflammation is usually considered as harmful; however, it is also necessary for tissue
recovery after injury. Macrophages exert immune and nonimmune functions throughout this …

The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

BS Hanna, G Wang, S Galván-Peña, AO Mann… - Immunity, 2023 - cell.com
Specific microbial signals induce the differentiation of a distinct pool of RORγ+ regulatory T
(Treg) cells crucial for intestinal homeostasis. We discovered highly analogous populations …

[PDF][PDF] IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation

M Faas, N Ipseiz, J Ackermann, S Culemann… - Immunity, 2021 - cell.com
Alternatively activated macrophages (AAMs) contribute to the resolution of inflammation and
tissue repair. However, molecular pathways that govern their differentiation have remained …

Regulatory T cells license macrophage pro-resolving functions during atherosclerosis regression

M Sharma, MP Schlegel, MS Afonso, EJ Brown… - Circulation …, 2020 - Am Heart Assoc
Rationale: Regression of atherosclerosis is an important clinical goal; however, the
pathways that mediate the resolution of atherosclerotic inflammation and reversal of plaques …

Venn diagrams in bioinformatics

A Jia, L Xu, Y Wang - Briefings in bioinformatics, 2021 - academic.oup.com
Venn diagrams are widely used tools for graphical depiction of the unions, intersections and
distinctions among multiple datasets, and a large number of programs have been developed …

[HTML][HTML] The influence of omega-3 fatty acids on skeletal muscle protein turnover in health, disuse, and disease

C McGlory, PC Calder, EA Nunes - Frontiers in nutrition, 2019 - frontiersin.org
Ingestion of omega-3 fatty acids is known to exert favorable health effects on a number of
biological processes such as improved immune profile, enhanced cognition, and optimized …