[HTML][HTML] Conformational Dynamics and Stability of Bilayers Formed by Mycolic Acids from the Mycobacterium tuberculosis Outer Membrane

LA Savintseva, IS Steshin, AA Avdoshin, SV Panteleev… - Molecules, 2023 - mdpi.com
Bilayers of mycolic acids (MAs) form the outer membrane of Mycobacterium tuberculosis that
has high strength and extremely low permeability for external molecules (including …

[HTML][HTML] Free Energy Barriers for Passive Drug Transport through the Mycobacterium tuberculosis Outer Membrane: A Molecular Dynamics Study

IS Steshin, AV Vasyankin, EA Shirokova… - International Journal of …, 2024 - mdpi.com
The emergence of multi-drug-resistant tuberculosis strains poses a significant challenge to
modern medicine. The development of new antituberculosis drugs is hindered by the low …