Purpose Genetic and genomic health information increasingly informs routine clinical care
and treatment. This systematic review aimed to identify the barriers and facilitators to …

Inherited genetic mutations can significantly increase the risk for prostate cancer (PC), may
be associated with aggressive disease and poorer outcomes, and can have hereditary …

PURPOSE Germline testing (GT) is a central feature of prostate cancer (PCA) treatment,
management, and hereditary cancer assessment. Critical needs include optimized …

Existing guidance regarding clinically informed germline testing for patients with cancer is
effective for evaluation of classic hereditary cancer syndromes and established gene/cancer …

Germline genetic testing is now routinely recommended for patients with prostate cancer
(PCa) because of expanded guidelines and options for targeted treatments. However …

Simple Summary Tumor-suppressor genes are involved in DNA break repair through the
homologous recombination system and are widely known for their role in hereditary cancer …

Prostate cancer (PCa) is the most common non-cutaneous cancer in men in Europe and is
predicted to exhibit declining mortality in the European Union (EU) due to various recent …

Context Germline testing (GT) is increasingly impacting prostate cancer (PCa) management
and screening, with direct effects in urology, medical oncology, and radiation oncology. The …

Background Genetic counseling and germline testing have an increasingly important role for
patients with prostate cancer (PCa); however, recent data suggests they are underutilized …

PURPOSE Germline mutations in DNA repair genes are present in approximately 10% of
men with metastatic prostate cancer (mPC), and guidelines recommend genetic germline …