Recent advances in models, mechanisms, biomarkers, and interventions in cisplatin-induced acute kidney injury

SJ Holditch, CN Brown, AM Lombardi… - International journal of …, 2019 - mdpi.com
Cisplatin is a widely used chemotherapeutic agent used to treat solid tumours, such as
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …

The role of mitochondrial ROS in the aging brain

R Stefanatos, A Sanz - FEBS letters, 2018 - Wiley Online Library
The brain is the most complex human organ, consuming more energy than any other tissue
in proportion to its size. It relies heavily on mitochondria to produce energy and is made up …

Immune mechanisms linked to depression via oxidative stress and neuroprogression

N Bakunina, CM Pariante, PA Zunszain - Immunology, 2015 - Wiley Online Library
Emerging evidence suggests a significant role for inflammation and oxidative stress as main
contributors to the neuroprogression that is observed in major depressive disorder (MDD) …

[HTML][HTML] Selenium and tellurium in the development of novel small molecules and nanoparticles as cancer multidrug resistance reversal agents

E Domínguez-Álvarez, B Rácz, MA Marć… - Drug Resistance …, 2022 - Elsevier
Selenium is an essential trace element that is crucial for cellular antioxidant defense against
reactive oxygen species (ROS). Recently, many selenium-containing compounds have …

[HTML][HTML] TRPM2 channel-mediated cell death: An important mechanism linking oxidative stress-inducing pathological factors to associated pathological conditions

P Malko, LH Jiang - Redox biology, 2020 - Elsevier
Oxidative stress resulting from the accumulation of high levels of reactive oxygen species is
a salient feature of, and a well-recognised pathological factor for, diverse pathologies. One …

Autophagic programmed cell death by selective catalase degradation

L Yu, F Wan, S Dutta, S Welsh, ZH Liu… - Proceedings of the …, 2006 - National Acad Sciences
Autophagy plays a central role in regulating important cellular functions such as cell survival
during starvation and control of infectious pathogens. Recently, it has been shown that …

Biological action of singlet molecular oxygen from the standpoint of cell signaling, injury and death

J Fujii, Y Soma, Y Matsuda - Molecules, 2023 - mdpi.com
Energy transfer to ground state triplet molecular oxygen results in the generation of singlet
molecular oxygen (1O2), which has potent oxidizing ability. Irradiation of light, notably …

Neuroprotective effects of bioavailable polyphenol-derived metabolites against oxidative stress-induced cytotoxicity in human neuroblastoma SH-SY5Y cells

A González-Sarrías, MA Núñez-Sánchez… - Journal of agricultural …, 2017 - ACS Publications
Oxidative stress is involved in cell death in neurodegenerative diseases. Dietary
polyphenols can exert health benefits, but their direct effects on neuronal cells are debatable …

Cross-talk between singlet oxygen- and hydrogen peroxide-dependent signaling of stress responses in Arabidopsis thaliana

C Laloi, M Stachowiak… - Proceedings of the …, 2007 - National Acad Sciences
Upon a dark-to-light shift, the conditional fluorescent (flu) mutant of Arabidopsis releases
singlet oxygen (1O2) within the plastid compartment. Distinct sets of nuclear genes are …

Study of cytotoxic and apoptogenic properties of saffron extract in human cancer cell lines

J Tavakkol-Afshari, A Brook, SH Mousavi - Food and Chemical Toxicology, 2008 - Elsevier
Saffron (dried stigmas of Crocus sativus L.) has been used as a spice, food colorant and
medicinal plant for millennia. In this study cytotoxic effect of saffron extract was evaluated in …