Schrader, LA and JG Tasker. Presynaptic modulation by metabotropic glutamate receptors
of excitatory and inhibitory synaptic inputs to hypothalamic magnocellular neurons. J …

We used patch-clamp recordings in slice preparations from Sprague-Dawley rats to evaluate
responses of 20 spinal-projecting neurons in the dorsal paraventricular nucleus (PVN) to …

There is growing interest in anxiolytic and pro-social effects of the neuropeptide oxytocin
(OXT), but the underlying intraneuronal mechanisms are largely unknown. Here we …

Diabetes mellitus and the coexisting conditions and complications, including hypo-and
hyperglycemic events, obesity, high cholesterol levels, and many more, are devastating …

G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors in
the mammalian genome. They are activated by a multitude of different ligands that elicit …

The body temperature of mice is higher at night than during the day. We show here that
global deletion of acid-sensing ion channel 1a (ASIC1a) results in lower body temperature …

Noradrenaline (NA) is a major neurotransmitter that regulates many neuroendocrine and
sympathetic autonomic functions of the hypothalamic paraventricular nucleus (PVN) …

Glutamate and norepinephrine transmitter systems play critical roles in the synaptic control
of hypothalamic magnocellular neurones. We recently reported on a norepinephrine …

Orexins, also called hypocretins, are newly discovered hypothalamic peptides that are
thought to be involved in various physiological functions. In spite of the fact that orexin …

1. Intracellular recordings were obtained from neurones in the region of the paraventricular
nucleus in slices of rat hypothalamus. Glutamate microdrops were applied to the surface of …