Casein kinase 2 (CK2): A possible therapeutic target in acute myeloid leukemia
Ø Bruserud, H Reikvam - Cancers, 2023 - mdpi.com
Simple Summary Acute myeloid leukemia (AML) is an aggressive blood cancer disease that
can only be cured by intensive anticancer treatment, and for several patients, allogeneic …
can only be cured by intensive anticancer treatment, and for several patients, allogeneic …
In vitro insights into the influence of marrow mesodermal/mesenchymal progenitor cells on acute myelogenous leukemia and myelodysplastic syndromes
J Liesveld, J Galipeau - Stem Cells, 2023 - academic.oup.com
The study of marrow-resident mesodermal progenitors can provide important insight into
their role in influencing normal and aberrant hematopoiesis as occurs in acute myelogenous …
their role in influencing normal and aberrant hematopoiesis as occurs in acute myelogenous …
Inflammatory response mediates cross-talk with immune function and reveals clinical features in acute myeloid leukemia
FM Zhong, FY Yao, J Liu, HB Zhang, MY Li… - Bioscience …, 2022 - portlandpress.com
Accumulated genetic mutations are an important cause for the development of acute
myeloid leukemia (AML), but abnormal changes in the inflammatory microenvironment also …
myeloid leukemia (AML), but abnormal changes in the inflammatory microenvironment also …
In vitro and in vivo modeling of normal and leukemic bone marrow niches: cellular senescence contribution to leukemia induction and progression
MJ Salazar-Terreros, JP Vernot - International Journal of Molecular …, 2022 - mdpi.com
Cellular senescence is recognized as a dynamic process in which cells evolve and adapt in
a context dependent manner; consequently, senescent cells can exert both beneficial and …
a context dependent manner; consequently, senescent cells can exert both beneficial and …
Patients with Bacterial Sepsis Are Heterogeneous with Regard to Their Systemic Lipidomic Profiles
KA Mosevoll, BA Hansen, IM Gundersen, H Reikvam… - Metabolites, 2022 - mdpi.com
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. In the present study, we investigated the systemic/serum lipidomic …
response to infection. In the present study, we investigated the systemic/serum lipidomic …
Progenitor hierarchy of chronic myelomonocytic leukemia identifies inflammatory monocytic-biased trajectory linked to worse outcomes
Myeloblast expansion is a hallmark of disease progression and comprises CD34+
hematopoietic stem and progenitor cells (HSPC). How this compartment evolves during …
hematopoietic stem and progenitor cells (HSPC). How this compartment evolves during …
Systemic metabolomic profiles in adult patients with bacterial sepsis: characterization of patient heterogeneity at the time of diagnosis
KA Mosevoll, BA Hansen, IM Gundersen, H Reikvam… - Biomolecules, 2023 - mdpi.com
Sepsis is a dysregulated host response to infection that causes potentially life-threatening
organ dysfunction. We investigated the serum metabolomic profile at hospital admission for …
organ dysfunction. We investigated the serum metabolomic profile at hospital admission for …
Pretransplant systemic lipidomic profiles in allogeneic stem cell transplant recipients
KJ Hatfield, Ø Bruserud, H Reikvam - Cancers, 2022 - mdpi.com
Simple Summary Stem cell transplantation is used in the treatment of aggressive
hematological malignancies and consists of initial high-dose and potentially lethal …
hematological malignancies and consists of initial high-dose and potentially lethal …
Monocytic Differentiation in Acute Myeloid Leukemia Cells: Diagnostic Criteria, Biological Heterogeneity, Mitochondrial Metabolism, Resistance to and Induction by …
Ø Bruserud, F Selheim… - International Journal of …, 2024 - mdpi.com
We review the importance of monocytic differentiation and differentiation induction in non-
APL (acute promyelocytic leukemia) variants of acute myeloid leukemia (AML), a …
APL (acute promyelocytic leukemia) variants of acute myeloid leukemia (AML), a …
[HTML][HTML] Toll-like receptor 4 signaling in osteoblasts is required for load-induced bone formation in mice
In mature bone, NGF is produced by osteoblasts following mechanical loading and signals
through resident sensory nerves expressing its high affinity receptor, neurotrophic tyrosine …
through resident sensory nerves expressing its high affinity receptor, neurotrophic tyrosine …