Human T-cell leukaemia virus type I and adult T-cell leukaemia-lymphoma

K Ishitsuka, K Tamura - The Lancet Oncology, 2014 - thelancet.com
Adult T-cell leukaemia-lymphoma (ATL) is a malignancy of peripheral T lymphocytes caused
by human T-lymphotropic virus type I (HTLV-1), and its prognosis is poor. There are an …

Immunopathogenesis of HTLV-1-assoaciated myelopathy/tropical spastic paraparesis (HAM/TSP)

HT Fuzii, GA da Silva Dias, RJS de Barros, LFM Falcão… - Life sciences, 2014 - Elsevier
Human T-cell lymphotropic virus type 1 (HTLV-1) is associated with adult T-cell
leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis …

Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein

E Jaworski, A Narayanan, R Van Duyne… - Journal of Biological …, 2014 - ASBMB
Human T-lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia
and HTLV-1-associated myelopathy/tropical spastic paraparesis. The HTLV-1 transactivator …

[HTML][HTML] LncRNAs related key pathways and genes in ischemic stroke by weighted gene co-expression network analysis (WGCNA)

M Wang, L Wang, L Pu, K Li, T Feng, P Zheng, S Li… - Genomics, 2020 - Elsevier
Background Ischemic stroke (IS) was a significant public health concern and long-chain
noncoding RNAs (lncRNAs) were gaining particular importance in stroke biology, however …

Digital droplet PCR (ddPCR) for the precise quantification of human T-lymphotropic virus 1 proviral loads in peripheral blood and cerebrospinal fluid of HAM/TSP …

GS Brunetto, R Massoud, EC Leibovitch… - Journal of …, 2014 - Springer
An elevated human T cell lymphotropic virus 1 (HTLV)-1 proviral load (PVL) is the main risk
factor for developing HTLV-1-associated myelopathy/tropical spastic paraparesis …

HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells

N Araya, T Sato, H Ando, U Tomaru… - The Journal of …, 2014 - Am Soc Clin Investig
Human T-lymphotropic virus type 1 (HTLV-1) is linked to multiple diseases, including the
neuroinflammatory disease HTLV-1–associated myelopathy/tropical spastic paraparesis …

CSF CXCL10, CXCL9, and neopterin as candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis

T Sato, A Coler-Reilly, A Utsunomiya… - PLoS neglected …, 2013 - journals.plos.org
Background Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical
spastic paraparesis (HAM/TSP) is a rare chronic neuroinflammatory disease. Since the …

NK cells and monocytes modulate primary HTLV-1 infection

R Moles, S Sarkis, V Galli, M Omsland, M Artesi… - PLoS …, 2022 - journals.plos.org
We investigated the impact of monocytes, NK cells, and CD8+ T-cells in primary HTLV-1
infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type …

Human T cell leukemia virus type 1 infection of the three monocyte subsets contributes to viral burden in humans

MF de Castro-Amarante, CA Pise-Masison… - Journal of …, 2016 - Am Soc Microbiol
Because the viral DNA burden correlates with disease development, we investigated the
contribution of monocyte subsets (classical, intermediate, and nonclassical monocytes) to …

Immunopathogenesis of viral infections in neurological autoimmune disease

MA Habibi, F Nezhad Shamohammadi, T Rajaei… - BMC neurology, 2023 - Springer
Autoimmune diseases develop due to self-tolerance failure in recognizing self and non-self-
antigens. Several factors play a role in inducing autoimmunity, including genetic and …